SCHEMBL21246731

SCHEMBL21246731

CC(O)CC(=O)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718023 0.81
SCHEMBL26108395 0.79
SCHEMBL15756698 0.77 MLYCD (0.33)
SCHEMBL6545278 0.76 TSHR (0.38)
SCHEMBL28163566 0.76 MGAM (0.35)
3-Hydroxybutyric Acid, (+/-)- SCHEMBL21246677 0.74 PGD (0.36) MAPK1
SCHEMBL12540531 0.74 ALDH1A1 (0.33)
SCHEMBL11548096 0.73
SCHEMBL4447710 0.72 KDM4E (0.30)
SCHEMBL20511458 0.72 TRPA1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019104851-A4 BETA-HYDROXYBUTYRYL-AMINO ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF 刘成 2019-08-15 WO disclosed