Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 2/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21246867 | 0.88 | SMN1; SMN2 (0.45) | ADORA2BLMNAHPGDSYKMAPT | |
| SCHEMBL22569492 | 0.74 | JAK2 (0.37) | LMNAALDH1A1ALOX15CSNK2A2CSNK2A1 | |
| SCHEMBL21262261 | 0.70 | ADORA2B (0.47) | ADORA2BLMNABCAT2HPGDSYK | |
| SCHEMBL356160 | 0.64 | ADORA2B (1.00) | ADORA2BLMNAPIK3CDPOLBADORA3 | |
| SCHEMBL2830735 | 0.64 | ADORA2B (0.79) | ADORA2BLMNAPIK3CDPOLBADORA3 | |
| SCHEMBL30529493 | 0.63 | SMN1; SMN2 (0.46) | ADORA2BLMNAHPGDALDH1A1POLB | |
| SCHEMBL21246730 | 0.63 | CCR4 (0.39) | LMNAHPGDMAPTALDH1A1 | |
| SCHEMBL11635641 | 0.63 | ALDH1A1 (0.56) | LMNAMAPTALDH1A1 | |
| Ethane SCHEMBL11629623 | 0.63 | LMNA (0.46) | LMNAMAPTALDH1A1ALOX15CSNK2A2 | |
| SCHEMBL17163983 | 0.63 | ADORA2B (0.51) | ADORA2BLMNAALDH1A1POLBNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749672-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | Ontario Institute for Cancer Research (OICR) (CA) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019153080-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-08-15 | — | — | WO | disclosed |