SCHEMBL2124709

SCHEMBL2124709

NC(=O)C1=Cc2ccccc2C(=NNc2ccccc2)C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 9/20 0.43
▸ KMT2A Q03164 9/20 0.43
▸ NPC1 O15118 5/20 0.43
▸ RAB9A P51151 5/20 0.43
▸ GAA P10253 4/20 0.43
▸ GFER P55789 1/20 0.43
▸ MAPT P10636 8/20 0.41
▸ L3MBTL1 Q9Y468 4/20 0.41
▸ POLB P06746 3/20 0.41
▸ HSP90AA1 P07900 1/20 0.41
▸ VCP P55072 1/20 0.41
▸ ALDH1A1 P00352 6/20 0.38
▸ HTT P42858 3/20 0.38
▸ DEPTOR Q8TB45 1/20 0.37
▸ TDP1 Q9NUW8 3/20 0.37
▸ PLA2G1B P04054 1/20 0.36
▸ ATG4B Q9Y4P1 1/20 0.36
▸ FGFR1 P11362 1/20 0.33
▸ SRC P12931 1/20 0.33
▸ FGFR2 P21802 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21436312 0.89 MEN1 (0.48) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL340839 0.85 MEN1 (0.42) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL21436648 0.77 MEN1 (0.47) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL21436700 0.77 MEN1 (0.40) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL8102488 0.76 CDC25B (0.43) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL21436301 0.75 RAB9A (0.45) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL21436606 0.74 PLAU (0.41) KMT2ANPC1RAB9AMAPT
SCHEMBL21436581 0.74 RAB9A (0.51) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL13113970 0.74 MEN1 (0.40) MEN1KMT2ANPC1RAB9AGAA
SCHEMBL30544831 0.73 SMO (0.37) MEN1KMT2ANPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658928-B1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2019-03-27 — — EP claimed
US-9346963-B2 Surface-modified pigment preparations BASF SE (DE) 2016-05-24 — — US claimed
EP-2658928-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2013-11-06 — — EP claimed
US-20130289174-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2013-10-31 — — US claimed
WO-2012089516-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2012-07-05 — — WO claimed
EP-2658928-B1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2019-03-27 — — EP disclosed
US-9346963-B2 Surface-modified pigment preparations BASF SE (DE) 2016-05-24 — — US disclosed
US-8753550-B2 Surface-modified pigment compositions BASF SE (DE) 2014-06-17 — — US disclosed
EP-2658928-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2013-11-06 — — EP disclosed
US-20130289174-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2013-10-31 — — US disclosed
EP-2443201-B1 SURFACE-MODIFIED PIGMENT COMPOSITIONS BASF SE (DE) 2013-08-14 — — EP disclosed
WO-2012089516-A1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2012-07-05 — — WO disclosed
US-20120126184-A1 SURFACE-MODIFIED PIGMENT COMPOSITIONS BASF SE (DE) 2012-05-24 — — US disclosed
EP-2443201-A2 SURFACE-MODIFIED PIGMENT COMPOSITIONS BASF SE (DE) 2012-04-25 — — EP disclosed
WO-2010146034-A2 SURFACE-MODIFIED PIGMENT COMPOSITIONS BASF SE (DE) 2010-12-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120126184-A1 SURFACE-MODIFIED PIGMENT COMPOSITIONS NR2E3, CRY1, CHRNA7 MEN1 2542/4885KMT2A 4356/4885NPC1 1207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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