Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4416410 | 0.84 | MMP8 (0.54) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL14874446 | 0.82 | HTT (0.44) | MMP8ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9712250 | 0.82 | MMP8 (0.58) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL21834962 | 0.81 | TRPA1 (0.47) | MMP8ALDH1A1RECQLMAPTLMNA | |
| SCHEMBL21834963 | 0.81 | TRPA1 (0.47) | MMP8ALDH1A1RECQLMAPTLMNA | |
| SCHEMBL24236755 | 0.81 | TRPA1 (0.47) | MMP8ALDH1A1RECQLMAPTLMNA | |
| SCHEMBL27993636 | 0.81 | MMP8 (0.57) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL19329165 | 0.79 | MMP8 (0.56) | MMP8ALDH1A1RECQLPIN1MAPT | |
| SCHEMBL21835005 | 0.78 | TRPA1 (0.45) | MMP8ALDH1A1RECQLMAPTLMNA | |
| SCHEMBL21253227 | 0.78 | TRPA1 (0.45) | MMP8ALDH1A1RECQLMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110446698-B | Microbicidal quinoline (thio) carboxamide derivatives | 先正达参股股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-112770632-B | Fungicidal compositions | 先正达农作物保护股份公司 | 2022-12-27 | — | — | CN | disclosed |
| US-20220030867-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION AG (CH) | 2022-02-03 | — | — | US | disclosed |
| EP-3601228-B1 | MICROBIOCIDAL QUINOLINE (THIO)CARBOXAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2022-01-19 | — | — | EP | disclosed |
| CN-112770632-A | Fungicidal compositions | 先正达农作物保护股份公司 | 2021-05-07 | — | — | CN | disclosed |
| US-10952436-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-23 | — | — | US | disclosed |
| EP-3749660-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2020-12-16 | — | — | EP | disclosed |
| US-20200354321-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2020-11-12 | — | — | US | disclosed |
| US-20200354321-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2020-11-12 | — | — | US | disclosed |
| CN-111683933-A | Novel pyridine carboxamides | 巴斯夫欧洲公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-110446698-A | Microbicidal quinoline (thio) carboxamide derivatives | SYNGENTA PARTICIPATIONS AG | 2019-11-12 | — | — | CN | disclosed |
| WO-2019154663-A1 | NEW PYRIDINE CARBOXAMIDES | BASF SE (DE) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354321-A1 | NEW PYRIDINE CARBOXAMIDES | COX4I1, NQO2, NDUFS5 | MMP8 4386/4885ALDH1A1 429/4885RECQL 2562/4885 |
| US-10952436-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | IDO1, IFNG, TLR1 | MMP8 2366/4885ALDH1A1 877/4885RECQL 948/4885 |
| US-20220030867-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, CYP3A43 | MMP8 3269/4885ALDH1A1 3481/4885RECQL 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.