Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RAB7A | P51149 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247292 | 0.93 | RAB7A (0.54) | FABP4FABP5PDE4BPDE4DMEN1 | |
| SCHEMBL21247303 | 0.80 | PTPN1 (0.59) | MEN1KMT2ARAB7ANPC1RAB9A | |
| SCHEMBL21247392 | 0.77 | RAB7A (0.68) | PDE4BPDE4DMEN1KMT2ARAB7A | |
| SCHEMBL21247104 | 0.76 | MEN1 (0.54) | FABP4FABP5PDE4BPDE4DMEN1 | |
| SCHEMBL21261022 | 0.75 | FLT3 (0.58) | FABP4FABP5PDE4BPDE4DMEN1 | |
| SCHEMBL22680862 | 0.75 | MEN1 (0.69) | PDE4BPDE4DMEN1KMT2ARAB7A | |
| SCHEMBL21261092 | 0.74 | GLO1 (0.72) | MEN1KMT2ARAB7ANPC1RAB9A | |
| SCHEMBL21247339 | 0.74 | MEN1 (0.69) | PDE4BPDE4DMEN1KMT2ARAB7A | |
| SCHEMBL21261056 | 0.74 | RAB7A (0.48) | FABP4FABP5PDE4BPDE4DMEN1 | |
| SCHEMBL21260928 | 0.73 | RAB7A (0.47) | FABP4FABP5PDE4BPDE4DRAB7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749659-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |