Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | CFTR | P13569 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB7A | P51149 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247292 | 0.82 | RAB7A (0.54) | KMT2AMEN1LMNAKDM4EHTT | |
| SCHEMBL21247216 | 0.80 | FABP4 (0.48) | PTPN1KMT2AMEN1LMNAHTT | |
| SCHEMBL21247337 | 0.77 | PTPN1 (0.68) | PTPN1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL21247200 | 0.75 | PTPN1 (0.61) | PTPN1CFTRKMT2AMEN1LMNA | |
| SCHEMBL21247234 | 0.74 | PTPN1 (0.64) | PTPN1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL21261018 | 0.74 | PTPN1 (0.60) | PTPN1CFTRKMT2AMEN1LMNA | |
| SCHEMBL21261016 | 0.74 | PTPN1 (0.60) | PTPN1CFTRKMT2AMEN1LMNA | |
| SCHEMBL21260934 | 0.73 | PTPN1 (0.73) | PTPN1CFTRKMT2AMEN1LMNA | |
| SCHEMBL21247155 | 0.71 | PTPN1 (0.56) | PTPN1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL22655236 | 0.66 | PTPN1 (0.60) | PTPN1KMT2AMEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749659-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |