Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | RAB7A | P51149 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 4/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247392 | 0.86 | RAB7A (0.68) | FLT3RAB7APDE4BPDE4DRAB9A | |
| SCHEMBL21247290 | 0.82 | GLO1 (0.53) | FLT3RAB7ARORCFABP4FABP5 | |
| SCHEMBL22680862 | 0.82 | MEN1 (0.69) | FLT3RAB7APDE4BPDE4DRAB9A | |
| SCHEMBL21247200 | 0.81 | PTPN1 (0.61) | FLT3RAB7ARORCFABP4FABP5 | |
| SCHEMBL21247258 | 0.80 | RAB7A (0.57) | FLT3RAB7ARORCFABP4FABP5 | |
| SCHEMBL21261088 | 0.79 | RORC (0.47) | RAB7ARORCFABP4FABP5PDE4B | |
| SCHEMBL21247339 | 0.79 | MEN1 (0.69) | RAB7APDE4BPDE4DRAB9AMAPT | |
| SCHEMBL21247300 | 0.79 | NOD1 (0.47) | FLT3RAB7ARORCFABP4FABP5 | |
| SCHEMBL21247382 | 0.78 | RAB7A (0.80) | FLT3RAB7AFABP4FABP5RAB9A | |
| SCHEMBL21260928 | 0.75 | RAB7A (0.47) | RAB7ARORCFABP4FABP5PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-19 | — | — | US | disclosed |
| CN-111954668-A | Fused thiophene derivative and use thereof | 埃尼奥制药公司 | 2020-11-17 | — | — | CN | disclosed |
| WO-2019154950-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361924-A1 | FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | FLT3 1514/4885RAB7A 2283/4885RORC 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.