Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21248366 | 0.90 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19PKMMAOA | |
| SCHEMBL1758499 | 0.88 | PKM (0.48) | PKMTDP1P4HTMSRD5A2SRD5A1 | |
| SCHEMBL21324101 | 0.81 | EGLN1 (0.39) | MAOAMAOBALDH1A1KMT2APTK2B | |
| SCHEMBL30876088 | 0.78 | LMNA (0.45) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21248016 | 0.78 | LMNA (0.47) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A | |
| SCHEMBL30876057 | 0.78 | LMNA (0.47) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A | |
| SCHEMBL21247818 | 0.78 | LMNA (0.45) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A | |
| SCHEMBL30876060 | 0.76 | LMNA (0.45) | CYP1A2CYP2C19ALDH1A1KMT2ALMNA | |
| SCHEMBL21248131 | 0.73 | CYP1A2 (0.42) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL28473926 | 0.72 | CYP1A2 (0.41) | CYP1A2CYP2D6CYP2C19ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258354-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2025-03-25 | — | — | US | disclosed |
| EP-3749669-B3 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-111683950-B | AhR modulators | 伊迪亚生物科学有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-4219495-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3749669-B1 | AHR MODULATORS | IDEAYA BIOSCIENCES INC (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-20230039955-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2023-02-09 | — | — | US | disclosed |
| US-11407764-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-11407764-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2022-08-09 | — | — | US | disclosed |
| US-20210002297-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| US-20210002297-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2021-01-07 | — | — | US | disclosed |
| EP-3749669-A1 | AHR MODULATORS | Ideaya Biosciences, Inc. (US) | 2020-12-16 | — | — | EP | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| US-10815250-B2 | AhR modulators | IDEAYA BIOSCIENCES, INC. (US) | 2020-10-27 | — | — | US | disclosed |
| CN-111683950-A | AhR modulators | 伊迪亚生物科学有限公司 | 2020-09-18 | — | — | CN | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| US-20190270754-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. | 2019-09-05 | — | — | US | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019156987-A1 | AhR MODULATORS | IDEAYA BIOSCIENCES, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407764-B2 | AhR modulators | AHR, ARNT, RORB | CYP1A2 39/4885CYP2D6 123/4885CYP2C19 347/4885 |
| US-20230039955-A1 | AhR MODULATORS | AHR, ARNT, RORB | CYP1A2 38/4885CYP2D6 123/4885CYP2C19 342/4885 |
| US-12258354-B2 | AhR modulators | AHR, ARNT, RORB | CYP1A2 39/4885CYP2D6 123/4885CYP2C19 347/4885 |
| US-10815250-B2 | AhR modulators | AHR, ARNT, RORB | CYP1A2 39/4885CYP2D6 123/4885CYP2C19 347/4885 |
| US-20210002297-A1 | AhR MODULATORS | AHR, ARNT, RORB | CYP1A2 39/4885CYP2D6 123/4885CYP2C19 347/4885 |
| US-20190270754-A1 | AhR MODULATORS | AHR, ARNT, RORB | CYP1A2 39/4885CYP2D6 123/4885CYP2C19 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.