Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12679798 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL12681373 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL28910963 | 0.81 | ALDH1A1 (0.41) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL3843112 | 0.79 | CYP19A1 (0.39) | ALDH1A1HSD17B10ALOX15MAPTHTT | |
| SCHEMBL619469 | 0.77 | MAPT (0.43) | ALDH1A1HSD17B10KDM4EMAPTHTT | |
| SCHEMBL16984845 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL21248636 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL3849844 | 0.76 | CYP19A1 (0.37) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL1034013 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10ALOX15KDM4EMAPT | |
| SCHEMBL20763036 | 0.72 | HSD17B10 (0.54) | ALDH1A1HSD17B10ALOX15KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3749674-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-12-16 | — | — | EP | disclosed |
| US-20200369697-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2020-11-26 | — | — | US | disclosed |
| WO-2019157376-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369697-A1 | MOLYBDENUM OXO ALKYLIDENE COMPOUNDS, METHODS OF MAKING THE SAME AND USE THEREOF IN METATHESIS REACTIONS | MSRB3, MMAB, CYB5R3 | ALDH1A1 1160/4885HSD17B10 964/4885ALOX15 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.