Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | HTR3A | P46098 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810305 | 0.85 | NPC1 (0.42) | NPC1RAB9ALMNAHPGDMAPT | |
| SCHEMBL3859718 | 0.80 | HPGD (0.41) | NPC1RAB9ALMNAHPGDMAPT | |
| SCHEMBL24894643 | 0.74 | HAO1 (0.44) | NPC1RAB9ALMNAHPGDMAPT | |
| SCHEMBL11289053 | 0.72 | HPGD (0.52) | NPC1RAB9ALMNAHPGDMAPT | |
| SCHEMBL7674839 | 0.71 | HTR1A (0.50) | LMNAHPGDMAPTALDH1A1HAO1 | |
| SCHEMBL23845497 | 0.70 | PDGFRB (0.37) | NPC1RAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL31542120 | 0.70 | RAB9A (0.52) | NPC1RAB9ALMNAHPGDMAPT | |
| SCHEMBL13057071 | 0.68 | HTR1A (0.57) | LMNAHPGDMAPTALOX12HAO1 | |
| SCHEMBL16768825 | 0.68 | HTR1A (0.45) | NPC1RAB9AMAPTHAO1HTR1A | |
| SCHEMBL19234396 | 0.68 | HPGD (0.52) | NPC1RAB9ALMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119639837-A | Vortioxetine Process for the preparation of intermediates | 广东东阳光药业股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| EP-3762371-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF VORTIOXETINE AND SALTS THEREOF | Piramal Enterprises Limited (IN) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019155352-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF VORTIOXETINE AND SALTS THEREOF | Piramal Enterprises Limited (IN) | 2019-08-15 | — | — | WO | disclosed |