Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 9/20 | 0.40 |
| ▸ | HTR3A | P46098 | 9/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21665978 | 0.78 | PKM (0.37) | TDP1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29411684 | 0.75 | NPC1 (0.50) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL76793 | 0.75 | HAO1 (0.55) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL576257 | 0.75 | NPC1 (0.50) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL29475022 | 0.75 | HAO1 (0.55) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL9515924 | 0.74 | LMNA (0.45) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL21253047 | 0.74 | NPC1 (0.42) | HAO1HTR1AHTR3ACYP1A2ADRB2 | |
| SCHEMBL735441 | 0.73 | HSD17B10 (0.44) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL11325280 | 0.71 | HAO1 (0.43) | HAO1HTR1AHTR3ATP53TDP1 | |
| SCHEMBL11482988 | 0.71 | HAO1 (0.43) | HAO1HTR1AHTR3ATP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288015-A1 | M6PR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |