Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257797 | 0.76 | MEN1 (0.43) | AADATKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL21257793 | 0.69 | LMNA (0.40) | SLC6A2MAOAMAOBSLC6A4SLC6A3 | |
| SCHEMBL21257763 | 0.69 | ALDH1A1 (0.36) | SLC6A2SLC6A4HRH4SLC6A3HTR7 | |
| SCHEMBL21257759 | 0.69 | SLC6A2 (0.40) | KMT2AMEN1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7898062 | 0.69 | KCNH2 (0.44) | SLC6A2MAOAMAOBSLC6A4SLC6A3 | |
| SCHEMBL5001522 | 0.68 | BMPR1B (0.43) | AADATKMT2AMEN1HTR7CHRM1 | |
| SCHEMBL8551856 | 0.67 | SRD5A1 (0.45) | AADATKMT2AMEN1HTR7CHRM1 | |
| SCHEMBL21257760 | 0.67 | HTR5A (0.41) | SLC6A2MAOAMAOBSLC6A4HRH4 | |
| SCHEMBL21257758 | 0.66 | NOTUM (0.38) | AADATKMT2ANOTUM | |
| SCHEMBL21257766 | 0.64 | IKBKB (0.38) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154261-A1 | PYRIDINE DERIVATIVE RELATED TO KMD5 PATHWAY | 南京明德新药研发股份有限公司 | 2019-08-15 | — | — | WO | disclosed |