Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125266 | 0.93 | SERPINE1 (0.49) | SERPINE1MEN1KMT2AHRH3ACACB | |
| SCHEMBL2125439 | 0.92 | SERPINE1 (0.39) | SERPINE1MEN1KMT2ALMNAOGA | |
| SCHEMBL2126453 | 0.87 | MAPT (0.42) | MEN1KMT2AHPGDSMN1; SMN2KDM4E | |
| SCHEMBL2128389 | 0.87 | SERPINE1 (0.45) | SERPINE1MEN1KMT2AHRH3HPGD | |
| SCHEMBL2127281 | 0.85 | SIRT6 (0.41) | SERPINE1HRH3ACACBLMNASIRT6 | |
| SCHEMBL384302 | 0.85 | SERPINE1 (0.58) | SERPINE1MEN1KMT2AHRH3ACACB | |
| SCHEMBL2126449 | 0.85 | SERPINE1 (0.40) | SERPINE1MEN1KMT2AHRH3LMNA | |
| SCHEMBL2126439 | 0.83 | SIRT6 (0.41) | SERPINE1ACACBLMNAOGASIRT6 | |
| SCHEMBL2126360 | 0.80 | SERPINE1 (0.45) | SERPINE1MEN1KMT2AHRH3HPGD | |
| SCHEMBL2127257 | 0.80 | MAPT (0.42) | MEN1KMT2AHPGDSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |