Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126885 | 0.93 | SIRT6 (0.41) | SIRT6HRH3PIK3CDPIK3CASERPINE1 | |
| SCHEMBL2126439 | 0.91 | SIRT6 (0.41) | SIRT6PIK3CDPIK3CASERPINE1MAPT | |
| SCHEMBL2127785 | 0.87 | CCNC (0.40) | SIRT6HRH3MAPTLMNAHTT | |
| SCHEMBL2126153 | 0.85 | SERPINE1 (0.48) | SIRT6HRH3SERPINE1LMNAACACB | |
| SCHEMBL2125439 | 0.85 | SERPINE1 (0.39) | SIRT6SERPINE1MAPTLMNAHTT | |
| SCHEMBL2126816 | 0.84 | SIRT6 (0.41) | SIRT6PIK3CDPIK3CASERPINE1MAPT | |
| SCHEMBL2126453 | 0.83 | MAPT (0.42) | MAPTLMNAHTTSLC6A9 | |
| SCHEMBL2126718 | 0.80 | CCNC (0.40) | SIRT6HRH3MAPTLMNAHTT | |
| SCHEMBL2617857 | 0.80 | SIRT6 (0.41) | SIRT6HRH3PIK3CDPIK3CASERPINE1 | |
| SCHEMBL2120611 | 0.80 | SIRT6 (0.41) | SIRT6HRH3PIK3CDPIK3CASERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |