Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2127257 | 0.93 | MAPT (0.42) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2127941 | 0.88 | MEN1 (0.39) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2126153 | 0.87 | SERPINE1 (0.48) | SMN1; SMN2KMT2AMEN1KDM4EHPGD | |
| SCHEMBL2125439 | 0.85 | SERPINE1 (0.39) | MAPTKMT2AMEN1HTTLMNA | |
| SCHEMBL2127281 | 0.83 | SIRT6 (0.41) | MAPTSLC6A9HTTLMNA | |
| SCHEMBL2125198 | 0.81 | MEN1 (0.40) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2617858 | 0.81 | KMT2A (0.46) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2122947 | 0.81 | KMT2A (0.46) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2617798 | 0.81 | KMT2A (0.46) | MAPTSMN1; SMN2CYP2C9CYP2C19TP53 | |
| SCHEMBL2126439 | 0.81 | SIRT6 (0.41) | MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |