SCHEMBL21261989

SCHEMBL21261989

CCCCc1ccc(OC(=O)c2cc(CCCC)c(O)c(CCCC)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.49
THRA P10827 2/20 0.47
PRSS1 P07477 2/20 0.46
ACR P10323 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 3/20 0.46
MAPT P10636 2/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
RARB P10826 1/20 0.43
PLK1 P53350 1/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
PLA2G1B P04054 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19199596 0.87 NSD2 (0.56) PRSS1ACRNPC1MAPTLMNA
SCHEMBL874719 0.85 AKT1 (0.43) THRBPRSS1ACRSMN1; SMN2NPC1
SCHEMBL7951967 0.84 THRB (0.58) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL7210214 0.84 THRB (0.58) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL5665942 0.84 THRB (0.58) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL778221 0.84 THRB (0.58) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL13741155 0.83 KMT2A (0.46) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL27547306 0.82 ESR1 (0.56) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL11116193 0.81 SMN1; SMN2 (0.58) THRBTHRAPRSS1ACRSMN1; SMN2
SCHEMBL10922310 0.81 MDH1 (0.56) THRBTHRASMN1; SMN2NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370780-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MIYOSHI OIL & FAT CO., LTD. (JP) 2022-06-28 US disclosed
US-20190248766-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MIYOSHI OIL & FAT CO., LTD. (JP) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370780-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MMS19, INTS9, SRRM2 THRB 3878/4885THRA 1487/4885PRSS1 493/4885
US-20190248766-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MMS19, INTS9, SRRM2 THRB 3878/4885THRA 1487/4885PRSS1 493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.