⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2789718 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL3892675 | 0.97 | — | — | |
| Cyclopropane SCHEMBL28089739 | 0.91 | CHRM2 (0.36) | — | |
| SCHEMBL8400136 | 0.91 | CHRNB2 (0.36) | — | |
| SCHEMBL6207154 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL8413000 | 0.79 | ADRB2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL4960594 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL5074625 | 0.79 | ADRB2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL8415263 | 0.77 | ALDH1A1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL8415270 | 0.77 | ALDH1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087603-A1 | PROCESS FOR PREPARING A MODIFIED NATURAL RUBBER BY MEANS OF A MODIFIER | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2016-06-09 | — | — | WO | claimed |
| EP-2069354-B1 | Aza-benzofuranyl compounds and methods of use | GENENTECH INC (US) | 2011-11-02 | — | — | EP | claimed |
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240051952-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-02-15 | — | — | US | disclosed |
| US-11806409-B2 | Imaging methods using 18F-radiolabeled biologics | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-07 | — | — | US | disclosed |
| EP-3722291-B1 | INDOLINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF FIBROTIC DISEASES | RESPIVERT LTD (GB) | 2023-07-19 | — | — | EP | disclosed |
| EP-3722291-B1 | INDOLINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF FIBROTIC DISEASES | RESPIVERT LTD (GB) | 2023-07-19 | — | — | EP | disclosed |
| EP-4206184-A1 | PHENOL DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023086383-A1 | SELECT KRAS G12C INHIBITORS AND USES THEREOF | 1200 PHARMA LLC (US) | 2023-05-19 | — | — | WO | disclosed |
| US-5290942-A | Acetylcholinesterase inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| US-5252749-A | Binding to serotonin receptors 5HT3, 5HT1D and 5HT1B; hypotensive agents; cardiovascular and psychological disorders | ELF SANOFI (FR) | 1993-10-12 | — | — | US | disclosed |
| US-5206371-A | Acetylcholinesterase inhibitor | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-04-27 | — | — | US | disclosed |
| US-5180831-A | Acetylcholinesterase Inhibitors | GEORGIA TECH RESEARCH CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0487411-A1 | Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments | ROUSSEL UCLAF (FR) | 1992-05-27 | — | — | EP | disclosed |
| EP-0096299-B1 | HYDROXYIMINO AND ALKOXYIMINO DERIVATIVES OF 1,4-DIHYDROPYRIDINE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION THEREFROM | Pierrel S.p.A. (IT) | 1989-02-01 | — | — | EP | disclosed |
| US-4593027-A | 3-aryl-7-chloro-3,4-dihydroacridine-1,9(2H,10H)-dione 1-oximes and 1-hydrazone derivatives, their salts, a process for their preparation, agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-06-03 | — | — | US | disclosed |
| US-4508719-A | Hydroxyimino and alkoxyimino derivatives of 1,4-dihydropyridine and anti-hypertensive compositions | PIERREL S.P.A. (IT) | 1985-04-02 | — | — | US | disclosed |
| US-3951963-A | 0-(Substituted-aminoalkyl)-5-nitroimidazole-(2)-aldoximes | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |