Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 3/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2737293 | 0.79 | GABRA1 (0.50) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL30368289 | 0.73 | ERN1 (0.42) | CES2CES1CA3CA6CA5A | |
| SCHEMBL78147 | 0.73 | ERN1 (0.42) | CES2CES1CA3CA6CA5A | |
| SCHEMBL24724632 | 0.73 | TSHR (0.47) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL7627962 | 0.70 | CES2 (0.53) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL6222478 | 0.70 | CES2 (0.36) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL5506954 | 0.69 | ADRA2A (0.45) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL29597482 | 0.69 | ADRA2A (0.45) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL1201506 | 0.68 | CES2 (0.52) | CES2CES1ADRA2AADRA2BADRA2C | |
| SCHEMBL27588800 | 0.67 | CES2 (0.45) | CES2CES1ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019153080-A1 | INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF | ONTARIO INSTITUTE FOR CANCER RESEARCH (OICR) (CA) | 2019-08-15 | — | — | WO | disclosed |