Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2541466 | 0.99 | KDM4E (0.37) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL13515137 | 0.90 | KDM4E (0.36) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL2127854 | 0.84 | RAD52 (0.44) | KDM4EGAAMAPTRAD52ACACB | |
| Hydrochloric Acid SCHEMBL2532139 | 0.83 | RAD52 (0.43) | KDM4EGAAMAPTRAD52ACACB | |
| SCHEMBL13515131 | 0.83 | ACACB (0.36) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL5836635 | 0.79 | KDM4E (0.49) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL6544760 | 0.79 | LIPC (0.38) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL6838886 | 0.79 | MAPT (0.40) | KDM4EGAAMAPTGFERRAD52 | |
| SCHEMBL5836188 | 0.78 | LTA4H (0.46) | KDM4EGAAMAPTGFERRAD52 | |
| Hydrochloric Acid SCHEMBL6761631 | 0.78 | LIPC (0.37) | KDM4EGAAMAPTGFERRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8002847-B2 | Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes | L 'OREAL S.A. (FR) | 2011-08-23 | — | — | US | claimed |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL S.A. (FR) | 2010-11-04 | — | — | US | claimed |
| EP-2182914-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'Oreal (FR) | 2010-05-12 | — | — | EP | claimed |
| EP-2175830-A2 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'Oreal (FR) | 2010-04-21 | — | — | EP | claimed |
| WO-2009019383-A2 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL (FR) | 2009-02-12 | — | — | WO | claimed |
| WO-2009016061-A2 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | L'OREAL (FR) | 2009-02-05 | — | — | WO | claimed |
| EP-1428515-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; methods and uses | OREAL (FR) | 2008-07-02 | — | — | EP | claimed |
| EP-1428514-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | OREAL (FR) | 2007-09-19 | — | — | EP | claimed |
| EP-1559412-A1 | Keratinous fibre-dyeing composition containing an alcohol oxydase and a cationic oxidation base | L'OREAL (FR) | 2005-08-03 | — | — | EP | claimed |
| US-20040221400-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a monosaccharide or disaccharide, processes and uses | L'OREAL (FR) | 2004-11-11 | — | — | US | claimed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428509-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polyol; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428508-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a monosaccharide or disaccharide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428514-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, a tertiary paraphenylenediamine and a benzomorpholine coupler; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428505-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a cationic direct dye containing a heterocyclic group ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428506-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a polymere containing a fatty chain; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428507-A1 | Dyeing composition containing a tertiary cationic paraphenylendiamine and an organic diacid, process and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428517-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a vitamine derivative; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428515-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1428513-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a opacifying or pearlescent agent; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040221400-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and a monosaccharide or disaccharide, processes and uses | KRT18, DPM1, DSG1 | KDM4E 3092/4885GAA 2383/4885MAPT 1357/4885 |
| US-20100275388-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES COMPRISING A CATIONIC CELLULOSE ETHER, A WEAKLY OXYETHYLENATED SORBITAN FATTY ACID ESTER AND OXIDATION DYES | KRT18, KRTCAP2, FASN | KDM4E 318/4885GAA 2045/4885MAPT 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.