Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 9/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6761631 | 0.99 | LIPC (0.37) | LIPCLIPGMCHR1KDM4EGAA | |
| SCHEMBL6543991 | 0.83 | FFAR4 (0.40) | LIPCLIPGMCHR1FFAR4ACACB | |
| SCHEMBL6544420 | 0.83 | LIPG (0.36) | LIPCLIPGMCHR1FFAR4ACACB | |
| SCHEMBL6544772 | 0.82 | MAPT (0.46) | MAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3644145 | 0.80 | HRH3 (0.47) | KDM4EGAAMAPTRAD52SMN1; SMN2 | |
| SCHEMBL2126264 | 0.79 | KDM4E (0.38) | MCHR1KDM4EGAAMAPTGFER | |
| SCHEMBL3645553 | 0.79 | HRH3 (0.49) | KDM4EGAAMAPTRAD52SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2541466 | 0.78 | KDM4E (0.37) | MCHR1KDM4EGAAMAPTGFER | |
| SCHEMBL3647982 | 0.77 | ALDH1A1 (0.39) | MCHR1KDM4EGAAMAPTGFER | |
| SCHEMBL13515137 | 0.77 | KDM4E (0.36) | MCHR1KDM4EGAAMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | claimed |
| EP-1375480-A1 | Para-phenylene-diamine derivatives comprising a silyl substituted pyrrolidine group and their use for the colouring of keratinic fibres | L'OREAL (FR) | 2004-01-02 | — | — | EP | claimed |
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | L'OREAL S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
| EP-1375480-A1 | Para-phenylene-diamine derivatives comprising a silyl substituted pyrrolidine group and their use for the colouring of keratinic fibres | L'OREAL (FR) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040060127-A1 | Composition for dyeing keratin fibers, comprising at least one para-phenylenediamine derivative comprising a pyrrolidyl group substituted with a silyl radical | KRT18, VIM, CDC73 | LIPC 4189/4885LIPG 4555/4885MCHR1 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.