Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21243737 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6001705 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL29368058 | 0.86 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL1345542 | 0.82 | NPSR1 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL16733406 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL1346372 | 0.81 | NQO2 (0.48) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL4948906 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL21264527 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL4893031 | 0.78 | MAPT (0.71) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL29951458 | 0.78 | ALOX15 (0.58) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339189-B2 | DNA primase and gyrase inhibitors | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2022-05-24 | — | — | US | disclosed |
| US-20190248836-A1 | DNA PRIMASE AND GYRASE INHIBITORS | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190248836-A1 | DNA PRIMASE AND GYRASE INHIBITORS | TOP2A, TOP1, DNA2 | ALDH1A1 2809/4885MEN1 3341/4885KMT2A 2617/4885 |
| US-11339189-B2 | DNA primase and gyrase inhibitors | TOP2A, TOP1, DNA2 | ALDH1A1 2809/4885MEN1 3341/4885KMT2A 2617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.