SCHEMBL21243737

SCHEMBL21243737

CCOC(=O)c1[nH]c2ccc([N+](=O)[O-])cc2c1CCC(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55
NPY1R P25929 1/20 0.55
NPY2R P49146 1/20 0.55
MAPT P10636 5/20 0.50
KDM4E B2RXH2 3/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 2/20 0.50
HSD17B10 Q99714 1/20 0.50
NQO2 P16083 1/20 0.48
HTR6 P50406 2/20 0.48
FBP1 P09467 1/20 0.47
HTR1A P08908 1/20 0.47
DRD2 P14416 1/20 0.47
DRD4 P21917 1/20 0.47
HTR1D P28221 1/20 0.47
HTR1B P28222 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21264516 0.88 ALDH1A1 (0.51) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL6001705 0.88 ALDH1A1 (0.57) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL29368058 0.85 ALDH1A1 (0.61) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL16733406 0.83 ALDH1A1 (0.71) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL29617493 0.82 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDGAAHSD17B10
SCHEMBL21264669 0.82 ALDH1A1 (0.66) ALDH1A1KDM4EHPGDGAAHSD17B10
SCHEMBL4893031 0.81 MAPT (0.71) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL4948906 0.81 ALDH1A1 (0.57) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL1346372 0.80 NQO2 (0.48) ALDH1A1MEN1KMT2APOLBPKM
SCHEMBL29951458 0.79 ALOX15 (0.58) ALDH1A1MEN1KMT2APOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067484-A1 CRYSTAL FORMS AND SALTS OF SPIROBICYCLIC COMPOUND ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) 2025-04-03 WO claimed
CN-118603458-A Device and method for measuring rigidity of flexible structural member and azimuth under zero stress state 中国空间技术研究院 2024-09-06 CN claimed
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-25 US claimed
EP-3688155-B1 A UNIVERSAL PLATFORM FOR PREPARING AN INHIBITORY CHIMERIC ANTIGEN RECEPTOR (ICAR) IMMPACT BIO LTD (IL) 2023-01-04 EP claimed
CN-114597410-A Dry method pole piece and oil-containing diaphragm and manufacturing method thereof 李鑫 2022-06-07 CN claimed
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER Revolution Medicines, Inc. (US) 2026-05-28 US disclosed
US-20260143965-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT SAMSUNG DISPLAY CO LTD (KR) 2026-05-21 US disclosed
EP-4745675-A2 ELECTROPHOTOGRAPHIC IMAGE FORMING DEVICE AND CARTRIDGE Canon Kabushiki Kaisha (JP) 2026-05-20 EP disclosed
EP-3728285-B1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS SAGE THERAPEUTICS LLC (US) 2026-04-08 EP disclosed
US-12581819-B2 Display panel and method for manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-03-17 US disclosed
US-20260015212-A1 LIFTING MECHANISM FOR AN APPARATUS FOR LIFTING CONTRUCTION BOARDS, LIFTING APPARATUS COMPRISING SUCH A MECHANISM, LIFTING METHOD USING SUCH AN APPARATUS EDMA (FR) 2026-01-15 US disclosed
EP-4678847-A1 LIFTING MECHANISM FOR A BUILDING BOARD LIFTING APPARATUS, LIFTING APPARATUS COMPRISING SUCH A MECHANISM, LIFTING METHOD USING SUCH AN APPARATUS EDMA (FR) 2026-01-14 EP disclosed
EP-3082719-B1 DENTIFRICE COMPOSITION COMPRISING SPHERICAL FUSED ALUMNIUM OXIDE PARTICLES GlaxoSmithKline Consumer Healthcare UK IP Ltd (GB) 2022-03-23 EP disclosed
US-11280090-B2 Gypsum board suitable for wet or humid areas AHLSTROM-MUNKSJÖ OYJ (FI) 2022-03-22 US disclosed
US-20220084632-A1 CLINICAL CLASSFIERS AND GENOMIC CLASSIFIERS AND USES THEREOF VERACYTE, INC. 2022-03-17 US disclosed
US-20220075980-A1 DISPLAY DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-10 US disclosed
CN-114156313-A Display device 三星显示有限公司 2022-03-08 CN disclosed
US-20220024961-A1 METHODS AND COMPOUNDS FOR MODULATING THE SECRETION OR EXPRESSION OF ADHESION PROTEINS OR ANGIOPOIETINS OF CELLS PACIFIC ARROW LTD (CN) 2022-01-27 US disclosed
EP-3944025-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING DEVICE AND CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2022-01-26 EP disclosed
US-20190248836-A1 DNA PRIMASE AND GYRASE INHIBITORS B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2019-08-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248836-A1 DNA PRIMASE AND GYRASE INHIBITORS TOP2A, TOP1, DNA2 ALDH1A1 2809/4885MEN1 3341/4885KMT2A 2617/4885
US-20260144799-A1 COMPOSITION COMPRISING A FIRST RAS INHIBITOR, SECOND RAS INHIBITOR AND A SHP2 INHIBITOR FOR USE IN THE TREATMENT OF CANCER PDCD1, CD274, PTPN1 ALDH1A1 2666/4885MEN1 2727/4885KMT2A 1397/4885
US-20260015212-A1 LIFTING MECHANISM FOR AN APPARATUS FOR LIFTING CONTRUCTION BOARDS, LIFTING APPARATUS COMPRISING SUCH A MECHANISM, LIFTING METHOD USING SUCH AN APPARATUS TNNC1, MYL12A, CPT1B ALDH1A1 3306/4885MEN1 2263/4885KMT2A 1877/4885
US-12581819-B2 Display panel and method for manufacturing the same JUP, ITK, OR10J3 ALDH1A1 1499/4885MEN1 4177/4885KMT2A 2125/4885
US-20260143965-A1 LIGHT EMITTING ELEMENT, AMINE COMPOUND FOR THE LIGHT EMITTING ELEMENT, AND DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT NR2E3, NR2E1, NR0B2 ALDH1A1 525/4885MEN1 2792/4885KMT2A 1281/4885
US-20220024961-A1 METHODS AND COMPOUNDS FOR MODULATING THE SECRETION OR EXPRESSION OF ADHESION PROTEINS OR ANGIOPOIETINS OF CELLS TEK, FN1, MYL6 ALDH1A1 3028/4885MEN1 408/4885KMT2A 3497/4885
US-20240251664-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME NES, NFE2L2, NUCB2 ALDH1A1 264/4885MEN1 1237/4885KMT2A 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.