Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16733406 | 0.88 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL6001705 | 0.85 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL29951458 | 0.83 | ALOX15 (0.58) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL830378 | 0.82 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2351650 | 0.82 | GABRA1 (0.60) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4893031 | 0.81 | MAPT (0.71) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL830073 | 0.81 | KDM4E (0.54) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL1259124 | 0.81 | KDM4E (0.61) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL21243737 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2APOLBPKM | |
| SCHEMBL21264516 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003129-B1 | 1H-Pyrido[3,4-B]indol-1-one and 2,3,4,9-Tetrahydro-1H-Beta-Carbolin-1-one Derivatives | NERVIANO MEDICAL SCIENCES SRL (IT) | 2017-08-09 | — | — | EP | disclosed |
| EP-2003129-B1 | 1H-Pyrido[3,4-B]indol-1-one and 2,3,4,9-Tetrahydro-1H-Beta-Carbolin-1-one Derivatives | NERVIANO MEDICAL SCIENCES SRL (IT) | 2017-08-09 | — | — | EP | disclosed |
| EP-2003129-A1 | 1H-Pyrido[3,4-B]indol-1-one and 2,3,4,9-Tetrahydro-1H-Beta-Carbolin-1-one Derivatives | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-17 | — | — | EP | disclosed |
| EP-2003129-A1 | 1H-Pyrido[3,4-B]indol-1-one and 2,3,4,9-Tetrahydro-1H-Beta-Carbolin-1-one Derivatives | Nerviano Medical Sciences S.r.l. (IT) | 2008-12-17 | — | — | EP | disclosed |