Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125198 | 0.94 | MEN1 (0.40) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2128389 | 0.88 | SERPINE1 (0.45) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL2126453 | 0.88 | MAPT (0.42) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2125553 | 0.86 | SERPINE1 (0.36) | MAPTCYP2C9CYP2C19KDM4EMAPK1 | |
| SCHEMBL2127785 | 0.84 | CCNC (0.40) | MAPTCYP2C9CYP2C19GAAMAPK1 | |
| SCHEMBL2120688 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2617888 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2617814 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2127365 | 0.82 | SIRT6 (0.39) | MEN1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL2617765 | 0.81 | KMT2A (0.51) | MEN1KMT2AMAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443091-A1 | ANTHELMINTIC AGENTS AND THEIR USE | Intervet International B.V. (NL) | 2012-04-25 | — | — | EP | disclosed |
| WO-2010146083-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2010-12-23 | — | — | WO | disclosed |