SCHEMBL212666

SCHEMBL212666

[c]1cccc2cc3c(cc12)Cc1cc2ccccc2cc1-3

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TP53 P04637 2/20 0.34
TSHR P16473 2/20 0.34
MAPK1 P28482 2/20 0.34
HSD17B10 Q99714 2/20 0.34
KDM4E B2RXH2 2/20 0.34
NPC1 O15118 2/20 0.34
MAPT P10636 2/20 0.34
RAB9A P51151 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
CASP1 P29466 1/20 0.31
CASP7 P55210 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212668 0.96 MEN1 (0.34) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL30924248 0.80 MEN1 (0.46) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL1655232 0.80 MEN1 (0.46) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL17063430 0.79 MEN1 (0.33) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL217952 0.79 TP53 (0.35) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL217954 0.79 TSHR (0.38) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL18832 0.76 ALDH1A1 (0.36) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL814892 0.76 KDM4E (0.36) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL814890 0.76 TP53 (0.33) MEN1KMT2ATP53TSHRMAPK1
SCHEMBL6118212 0.76 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US claimed
US-9880469-B2 Resins for underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2018-01-30 US claimed
US-20160016872-A1 RESINS FOR UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-21 US claimed
US-11708434-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-07-25 US disclosed
WO-2023114813-A1 PROCESSES FOR MAKING PROPYLENE-BASED COPOLYMERS HAVING BROAD CDS AND MWDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-06-22 WO disclosed
US-11142593-B2 Lecithin quenching agent EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-10-12 US disclosed
US-20210277154-A1 Silica Quenching Agents for use in Polymerization Process EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-09-09 US disclosed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US disclosed
US-11046793-B2 Silica quenching agents for use in polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-29 US disclosed
US-11041029-B2 Aluminum alkyls with pendant olefins for polyolefin reactions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-22 US disclosed
US-10941228-B2 Polymerization processes using high molecular weight polyhydric quenching agents EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-03-09 US disclosed
WO-2005113622-A1 MULTIPLE CATALYST AND REACTOR SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-12-01 WO disclosed
WO-2005108442-A1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-17 WO disclosed
WO-2005075524-A1 ANALYSIS METHOD FOR OLEFIN POLYMERISATION CATALYSTS USING UV LUMINESCENCE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
EP-1558655-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2005-08-03 EP disclosed
US-20050158864-A1 Analysis method EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US disclosed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US disclosed
US-20040127614-A1 a Dot T-Peel of 1 Newton or more on Kraft paper; molecualr weight of 10,000 to 100,000; and a branching index (g') of 0.98 or less EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US disclosed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160016872-A1 RESINS FOR UNDERLAYERS AS3MT, TET2, MMAB MEN1 4482/4885KMT2A 250/4885TP53 3064/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.