SCHEMBL217954

SCHEMBL217954

[c]1cccc2c1-c1cc3ccccc3cc1C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP3A4 P08684 3/20 0.38
TP53 P04637 3/20 0.38
MAPK1 P28482 3/20 0.38
HSD17B10 Q99714 3/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP2D6 P10635 2/20 0.38
CYP2C9 P11712 2/20 0.38
PKM P14618 2/20 0.38
CYP2C19 P33261 2/20 0.38
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
LMNA P02545 1/20 0.34
CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL814892 0.97 KDM4E (0.36) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL23194 0.79 MAOA (0.46) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL212668 0.79 MEN1 (0.34) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL212666 0.79 MEN1 (0.34) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL1655232 0.76 MEN1 (0.46) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL30924248 0.76 MEN1 (0.46) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL7765422 0.76 MAOA (0.35) TSHRCYP3A4HSD17B10MAOA
SCHEMBL217952 0.75 TP53 (0.35) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL4867512 0.75 SMN1; SMN2 (0.42) TSHRKDM4EMAPTSMN1; SMN2CYP3A4
SCHEMBL27473125 0.74 METAP1 (0.41) KDM4EMAPTSMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220131092-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2022-04-28 US claimed
CN-109906234-B Single site catalyst polyolefin polymerization process 埃克森美孚化学专利公司 2022-04-22 CN claimed
US-20210328150-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, ORGANIC ELECTROLUMINESCENT MATERIAL COMPRISING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US claimed
CN-113493422-A Organic electroluminescent compound, organic electroluminescent material comprising same, and organic electroluminescent device 罗门哈斯电子材料韩国有限公司 2021-10-12 CN claimed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US claimed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US claimed
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2024-06-06 US disclosed
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-05-30 US disclosed
CN-117903127-A Organic electroluminescent compound, various host materials, and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-04-19 CN disclosed
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-18 US disclosed
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-04-16 US disclosed
US-20240114777-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-04 US disclosed
US-20240114778-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-04-04 US disclosed
WO-2005075524-A1 ANALYSIS METHOD FOR OLEFIN POLYMERISATION CATALYSTS USING UV LUMINESCENCE EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-08-18 WO disclosed
EP-1558655-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2005-08-03 EP disclosed
US-20050158864-A1 Analysis method EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-21 US disclosed
US-20040220359-A1 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2004-11-04 US disclosed
US-20040138392-A1 polyolefin adhesives; to produce reactor blends (also called intimate blends) of various polymers and other polymer compositions. EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-15 US disclosed
US-20040127614-A1 a Dot T-Peel of 1 Newton or more on Kraft paper; molecualr weight of 10,000 to 100,000; and a branching index (g') of 0.98 or less EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US disclosed
WO-2004046214-A2 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-06-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, SOD1, NECTIN4 TSHR 4813/4885KDM4E 2591/4885MAPT 3004/4885
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 TSHR 3895/4885KDM4E 2414/4885MAPT 1602/4885
US-11963439-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same OR10J3, VDAC2, ICOSLG TSHR 4702/4885KDM4E 892/4885MAPT 1032/4885
US-20240114777-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, NECTIN4, EPCAM TSHR 4776/4885KDM4E 2543/4885MAPT 2286/4885
US-20240188424-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, L1CAM, EPCAM TSHR 4697/4885KDM4E 2913/4885MAPT 2316/4885
US-20240130230-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, TERT, ELAVL1 TSHR 4713/4885KDM4E 1891/4885MAPT 1563/4885
US-20240114778-A1 ORGANIC ELECTROLUMINESCENT COMPOUND, A PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME OR10J3, ELAVL1, EML4 TSHR 4769/4885KDM4E 2500/4885MAPT 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.