Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL217952 | 0.97 | TP53 (0.35) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL4824234 | 0.79 | MAPT (0.46) | TSHRHSD17B10ALDH1A1HPGDKDM4E | |
| SCHEMBL814892 | 0.77 | KDM4E (0.36) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL23903 | 0.76 | MAOA (0.41) | HSD17B10ALDH1A1HPGDCASP7KDM4E | |
| SCHEMBL212666 | 0.76 | MEN1 (0.34) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL212668 | 0.76 | MEN1 (0.34) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL4648343 | 0.75 | CDC25B (0.33) | TSHR | |
| SCHEMBL17063463 | 0.75 | MEN1 (0.32) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL4851856 | 0.74 | SMN1; SMN2 (0.52) | TP53TSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL27626677 | 0.74 | MAOA (0.40) | HSD17B10ALDH1A1HPGDCASP7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539993-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-08 | — | — | US | disclosed |
| US-9834628-B2 | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150025207-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-08-09 | — | — | US | disclosed |
| US-8173828-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-05-08 | — | — | US | disclosed |
| EP-1833859-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-09-19 | — | — | EP | disclosed |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| WO-2006065843-A2 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | TP53 3031/4885TSHR 1993/4885MAPK1 1732/4885 |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | B2M, CDYL, MLX | TP53 4126/4885TSHR 2843/4885MAPK1 3706/4885 |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | TP53 1181/4885TSHR 47/4885MAPK1 2473/4885 |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | MLX, AP1M1, AP2M1 | TP53 2752/4885TSHR 2259/4885MAPK1 1102/4885 |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | AP2M1, AP1M1, CPNE4 | TP53 2362/4885TSHR 1486/4885MAPK1 1418/4885 |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | CPNE4, TIMM13, NECTIN4 | TP53 985/4885TSHR 4546/4885MAPK1 4406/4885 |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | ZKSCAN2, ZRANB2, ZC3H18 | TP53 1504/4885TSHR 1891/4885MAPK1 2061/4885 |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | OR10J3, ZRANB2, SLC39A3 | TP53 1281/4885TSHR 1942/4885MAPK1 2184/4885 |
| US-20120202956-A1 | Halogen Substituted Heteroatom-Containing Metallocene Compounds for Olefin Polymerization | OPRM1, POLM, AP1M1 | TP53 3031/4885TSHR 1993/4885MAPK1 1732/4885 |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | OSBP, OSBPL3, OSBP2 | TP53 4551/4885TSHR 4116/4885MAPK1 1866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.