SCHEMBL2126754

SCHEMBL2126754

CC1(C)C(CO)C1C(=O)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
LMNA P02545 1/20 0.47
ADRA2A P08913 1/20 0.47
CNR1 P21554 1/20 0.47
ATM Q13315 1/20 0.47
FABP7 O15540 1/20 0.46
FABP5 Q01469 1/20 0.46
MAPK1 P28482 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 4/20 0.43
TSHR P16473 2/20 0.43
GAA P10253 1/20 0.43
PKM P14618 1/20 0.43
FKBP1A P62942 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2127178 0.86 TDP1 (0.67) TDP1L3MBTL1LMNAADRA2ACNR1
SCHEMBL2128100 0.84 FABP7 (0.48) ALDH1A1ATMFABP7FABP5
SCHEMBL6441324 0.81 ALDH1A1 (0.51) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL11317892 0.80 ALDH1A1 (0.54) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL472949 0.78 TDP1 (0.58) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL1072373 0.77 TDP1 (0.46) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL1153506 0.77 TP53 (0.43) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL1072369 0.77 TDP1 (0.46) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL15996432 0.77 ALDH1A1 (0.46) ALDH1A1TDP1L3MBTL1LMNAADRA2A
SCHEMBL3681480 0.77 TDP1 (0.57) ALDH1A1TDP1L3MBTL1LMNAADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
CN-100341842-C Process for production of formylcyclopropanecarboxylic ester compound SUMITOMO CHEMICAL CO (JP) 2007-10-10 CN disclosed
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-10-27 US disclosed
CN-1668570-A Process for producing formylcyclopropanecarboxylic acid ester compound SUMITOMO CHEMICAL CO (JP) 2005-09-14 CN disclosed
EP-1535895-A1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS Sumitomo Chemical Company, Limited (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester AHCYL1, HACL2, CBR1 ALDH1A1 1604/4885TDP1 4597/4885L3MBTL1 3477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.