SCHEMBL2128100

SCHEMBL2128100

COc1ccc(COC(=O)C2C(CO)C2(C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FABP7 O15540 1/20 0.48
FABP5 Q01469 1/20 0.48
ALDH1A1 P00352 1/20 0.45
HTT P42858 1/20 0.42
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MMP9 P14780 2/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.40
MMP12 P39900 1/20 0.40
ATM Q13315 1/20 0.40
P2RX4 Q99571 1/20 0.40
FFAR1 O14842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126754 0.84 ALDH1A1 (0.49) FABP7FABP5ALDH1A1ATM
SCHEMBL2128290 0.80 FABP7 (0.47) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL6408318 0.79 ALDH1A1 (0.42) FABP7FABP5ALDH1A1HTTPOLB
SCHEMBL6407683 0.77 MMP1 (0.44) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL2127178 0.75 TDP1 (0.67) MMP9MMP1MMP2MMP12ATM
SCHEMBL292835 0.73 NPC1 (0.59) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL2126626 0.73 FABP7 (0.49) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL28976447 0.73 FABP7 (0.49) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL8502974 0.73 FABP7 (0.58) FABP7FABP5ALDH1A1HTTNPC1
SCHEMBL8191635 0.73 FABP7 (0.58) FABP7FABP5ALDH1A1HTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-10-27 US disclosed
EP-1535895-A1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS Sumitomo Chemical Company, Limited (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester AHCYL1, HACL2, CBR1 FABP7 1553/4885FABP5 1789/4885ALDH1A1 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.