Glutamic Acid

Glutamic Acid

SCHEMBL21268582

CN=C=O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.69
GRM6 O15303 2/20 0.69
GRM7 Q14831 2/20 0.69
GRM4 Q14833 2/20 0.69
CYP1A2 P05177 2/20 0.69
GRIN2D O15399 1/20 0.69
GRIN3B O60391 1/20 0.69
GSR P00390 1/20 0.69
GRIK1 P39086 1/20 0.69
GRM5 P41594 1/20 0.69
GRIA1 P42261 1/20 0.69
GRIA2 P42262 1/20 0.69
GRIA3 P42263 1/20 0.69
SLC1A3 P43003 1/20 0.69
SLC1A2 P43004 1/20 0.69
SLC1A1 P43005 1/20 0.69
GRIA4 P48058 1/20 0.69
GRIN1 Q05586 1/20 0.69
GRIN2A Q12879 1/20 0.69
GRIK2 Q13002 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL27994004 0.86 GRM8 (0.86) GRM8GRM6GRM7GRM4CYP1A2
D-Glutamate SCHEMBL9449715 0.83 GRM8 (0.90) GRM8GRM6GRM7GRM4CYP1A2
Glutamic Acid SCHEMBL7965611 0.83 GRM8 (0.90) GRM8GRM6GRM7GRM4CYP1A2
D-Glutamate SCHEMBL27721208 0.83 GRM8 (0.90) GRM8GRM6GRM7GRM4CYP1A2
Glutamic Acid SCHEMBL639610 0.83 GRM8 (0.90) GRM8GRM6GRM7GRM4CYP1A2
D-Glutamate SCHEMBL17127348 0.83 GRM8 (1.00) GRM8GRM6GRM7GRM4CYP1A2
D-Glutamate SCHEMBL1330484 0.83 GRM8 (1.00) GRM8GRM6GRM7GRM4CYP1A2
Glutamic Acid SCHEMBL5704264 0.83 GRM8 (1.00) GRM8GRM6GRM7GRM4CYP1A2
D-Glutamate SCHEMBL1330824 0.83 GRM8 (1.00) GRM8GRM6GRM7GRM4CYP1A2
Glutamic Acid SCHEMBL1554237 0.83 GRM8 (1.00) GRM8GRM6GRM7GRM4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3527593-B1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-23 EP disclosed
CN-109790269-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2022-06-14 CN disclosed
US-11118001-B2 Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-09-14 US disclosed
US-11078321-B2 2021-08-03 US disclosed
CN-112979917-A Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2021-06-18 CN disclosed
US-20200048403-A1 ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-13 US disclosed
EP-3527593-A1 ISOCYANATE COMPOSITION, PRODUCTION METHOD FOR ISOCYANATE COMPOSITION, AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-08-21 EP disclosed
CN-109790269-A Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2019-05-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078321-B2 IDH3A, IPO4, F12 GRM8 2987/4885GRM6 2524/4885GRM7 1976/4885
US-11118001-B2 Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer IDH3A, IPO4, IDH3B GRM8 3187/4885GRM6 2156/4885GRM7 1880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.