Glutamic Acid

Glutamic Acid

SCHEMBL5704264

N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 1.00
GRM6 O15303 2/20 1.00
GRM7 Q14831 2/20 1.00
GRM4 Q14833 2/20 1.00
GRIN2D O15399 1/20 1.00
GRIN3B O60391 1/20 1.00
GSR P00390 1/20 1.00
CYP1A2 P05177 1/20 1.00
GRIK1 P39086 1/20 1.00
GRM5 P41594 1/20 1.00
GRIA1 P42261 1/20 1.00
GRIA2 P42262 1/20 1.00
GRIA3 P42263 1/20 1.00
SLC1A3 P43003 1/20 1.00
SLC1A2 P43004 1/20 1.00
SLC1A1 P43005 1/20 1.00
GRIA4 P48058 1/20 1.00
GRIN1 Q05586 1/20 1.00
GRIN2A Q12879 1/20 1.00
GRIK2 Q13002 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1554237 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL2201 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332297 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330484 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL248800 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL931953 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL410241 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330824 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL17127348 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332144 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688966-A1 A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION COMPRISING TWO TYPES OF CORROSION INHIBITORS BASF SE (DE) 2014-01-29 EP disclosed
WO-2012127399-A1 A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION COMPRISING TWO TYPES OF CORROSION INHIBITORS BASF SE (DE) 2012-09-27 WO disclosed
EP-1689429-A1 BIOMARKERS FOR THE EFFICACY OF SOMATOSTATIN ANALOGUE TREATMENT Novartis AG (CH) 2006-08-16 EP disclosed
EP-1682665-A2 USE OF FIBROBLAST GROWTH FACTOR FRAGMENTS Novartis AG (CH) 2006-07-26 EP disclosed
WO-2005053732-A1 BIOMARKERS FOR THE EFFICACY OF SOMATOSTATIN ANALOGUE TREATMENT NOVARTIS AG (CH) 2005-06-16 WO disclosed
WO-2005045044-A2 USE OF FIBROBLAST GROWTH FACTOR FRAGMENTS NOVARTIS AG (CH) 2005-05-19 WO disclosed