Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503308 | 0.82 | PLA2G4B (0.58) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2628188 | 0.82 | POLB (0.59) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10492444 | 0.81 | NQO1 (0.50) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2528810 | 0.81 | PLA2G4B (0.56) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6709316 | 0.81 | NQO1 (0.54) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2528806 | 0.81 | ALDH1A1 (0.54) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL700166 | 0.81 | PARP10 (0.61) | NQO1PARP10ALDH1A1KDM4ETDP1 | |
| SCHEMBL10884546 | 0.81 | NQO1 (0.54) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27661058 | 0.80 | NQO1 (0.48) | NQO1PARP10SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5257976 | 0.80 | HTT (0.63) | SMN1; SMN2NPC1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1544196-B1 | PROCESS FOR THE PRODUCTION OF GAMMA-KETO ACETALS | DAIICHI SANKYO CO LTD (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-7176323-B2 | Process for the production of γ-keto acetals | SANKYO COMPANY, LIMITED (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050148780-A1 | Process for the production of gamma-keto acetals | SANKYO COMPANY, LIMITED (JP) | 2005-07-07 | — | — | US | disclosed |
| EP-1544196-A1 | PROCESS FOR THE PRODUCTION OF GAMMA-KETO ACETALS | Sankyo Company, Limited (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148780-A1 | Process for the production of gamma-keto acetals | AKR1A1, AKR1D1, AKR1B1 | NQO1 711/4885PARP10 1310/4885SMN1; SMN2 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.