Sugi Predict

Sugi Predict / Compounds / SCHEMBL21272272

SCHEMBL21272272

SCHEMBL21272272

C[Si]1(C)C=C(c2ccccc2)C(c2ccccc2)=C1c1cccnc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 6/20 0.42
▸ ALDH1A1 P00352 4/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP3A4 P08684 1/20 0.42
▸ CYP19A1 P11511 3/20 0.39
▸ KDM4E B2RXH2 4/20 0.39
▸ RAB9A P51151 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ MAPT P10636 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ HPGD P15428 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ LMNA P02545 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPY5R Q15761 2/20 0.37
▸ CYP2E1 P05181 1/20 0.37
▸ CYP2B6 P20813 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7116118 0.78 CYP2A6 (0.50) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL6257554 0.78 CYP2A6 (0.45) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL28378194 0.77 HPGDS (0.45) CYP2A6ALDH1A1CYP1A2CYP19A1KDM4E
SCHEMBL21272268 0.76 KDM4E (0.41) CYP2A6ALDH1A1CYP1A2CYP19A1KDM4E
SCHEMBL6256350 0.76 CYP2A6 (0.47) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL21272273 0.75 CYP2A6 (0.38) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL7122781 0.74 CYP2A6 (0.45) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL7123038 0.74 CYP2A6 (0.45) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL8331715 0.73 CYP2A6 (0.44) CYP2A6ALDH1A1CYP1A2CYP3A4CYP19A1
SCHEMBL13777178 0.72 KDM4E (0.32) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 — — CN disclosed
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 — — CN disclosed
CN-109863155-B Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 — — CN disclosed
CN-110049990-B Polycyclic aromatic amino compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 — — CN disclosed
US-11407774-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-08-09 — — US disclosed
CN-107531641-B Material for transporting electrons, organic electroluminescent element, and display device or lighting device 爱思开新材料捷恩智株式会社 2022-03-15 — — CN disclosed
CN-111662314-B Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-10-26 — — CN disclosed
CN-112210368-A Composition for forming light-emitting layer, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-01-12 — — CN disclosed
CN-106905367-B Electron transport material or electron injection material, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-17 — — CN disclosed
CN-111909189-A Polycyclic aromatic compound, multimer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-10 — — CN disclosed
CN-108473511-B Polycyclic aromatic compound, material for organic device, light-emitting element, and device 学校法人关西学院 2020-11-06 — — CN disclosed
CN-111892615-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-06 — — CN disclosed
CN-107406759-B Polycyclic aromatic compound, composition for forming light-emitting layer, and use thereof 学校法人关西学院 2020-10-30 — — CN disclosed
CN-105431439-B Polycyclic aromatic compound, method for producing same, material for organic device, and application thereof 学校法人关西学院 2020-09-25 — — CN disclosed
CN-111662314-A Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-09-15 — — CN disclosed
CN-111527094-A Compound having boron as spiro atom and polymer compound thereof 学校法人关西学院 2020-08-11 — — CN disclosed
CN-111212844-A Polycyclic aromatic dimer compound 学校法人关西学院 2020-05-29 — — CN disclosed
CN-107735879-B Polycyclic aromatic compound, polycyclic aromatic polymer compound, composition for forming light-emitting layer, and use thereof 学校法人关西学院 2020-03-13 — — CN disclosed
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11407774-B2 Polycyclic aromatic compound ETV6, EML4, EBPL CYP2A6 3848/4885ALDH1A1 3563/4885CYP1A2 3501/4885
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, EBPL CYP2A6 3848/4885ALDH1A1 3563/4885CYP1A2 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.