Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17008153 | 0.82 | CYP2A6 (0.43) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL28377734 | 0.78 | RXFP1 (0.36) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL21272265 | 0.76 | KDM4E (0.39) | ALDH1A1NPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL16685271 | 0.75 | CYP2A6 (0.54) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL21272272 | 0.75 | CYP2A6 (0.42) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL23242620 | 0.73 | CYP2A6 (0.52) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL28122684 | 0.73 | CYP2A6 (0.52) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL28377175 | 0.70 | KDM4E (0.43) | ALDH1A1NPC1TP53SMN1; SMN2MAPT | |
| SCHEMBL28431976 | 0.69 | ACLY (0.53) | CYP2A6ALDH1A1NPC1RAB9ATP53 | |
| SCHEMBL13785062 | 0.66 | CYP2A6 (0.47) | CYP2A6ALDH1A1NPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407774-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2022-08-09 | — | — | US | disclosed |
| US-20190256538-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407774-B2 | Polycyclic aromatic compound | ETV6, EML4, EBPL | CYP2A6 3848/4885ALDH1A1 3563/4885NPC1 1305/4885 |
| US-20190256538-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EML4, EBPL | CYP2A6 3848/4885ALDH1A1 3563/4885NPC1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.