Sugi Predict

Sugi Predict / Compounds / SCHEMBL21272268

SCHEMBL21272268

SCHEMBL21272268

C[Si]1(C)C=C(c2ccccc2)C(c2ccccc2)=C1c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.41
▸ LMNA P02545 7/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CCR1 P32246 2/20 0.41
▸ CCR5 P51681 2/20 0.41
▸ CCR8 P51685 2/20 0.41
▸ HIF1A Q16665 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ METAP1 P53582 1/20 0.41
▸ BLM P54132 1/20 0.41
▸ DOHH Q9BU89 1/20 0.41
▸ P4HTM Q9NXG6 1/20 0.41
▸ CYP2A6 P11509 1/20 0.39
▸ SMN1; SMN2 Q16637 7/20 0.37
▸ RAB9A P51151 7/20 0.37
▸ NPC1 O15118 5/20 0.37
▸ TP53 P04637 5/20 0.37
▸ PKM P14618 3/20 0.37
▸ NPY5R Q15761 1/20 0.37
▸ L3MBTL1 Q9Y468 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28373651 0.92 KDM4E (0.49) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL28378194 0.87 HPGDS (0.45) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL7116753 0.80 KDM4E (0.46) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL7778273 0.79 KDM4E (0.42) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL6254371 0.79 KDM4E (0.42) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL21272272 0.76 CYP2A6 (0.42) KDM4ELMNACYP1A2CYP2A6SMN1; SMN2
SCHEMBL6252273 0.74 KDM4E (0.41) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL6267426 0.74 CYP1A2 (0.43) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL6266204 0.72 CYP1A2 (0.44) KDM4ELMNACYP1A2CCR1CCR5
SCHEMBL35754 0.72 KDM4E (0.68) KDM4ELMNACYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111527094-B Compound, polymer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-03-26 — — CN disclosed
CN-111212844-B Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2023-08-25 — — CN disclosed
CN-109863155-B Polycyclic aromatic compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 — — CN disclosed
CN-110049990-B Polycyclic aromatic amino compound, material for organic element, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-13 — — CN disclosed
US-11407774-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-08-09 — — US disclosed
CN-107531641-B Material for transporting electrons, organic electroluminescent element, and display device or lighting device 爱思开新材料捷恩智株式会社 2022-03-15 — — CN disclosed
CN-111662314-B Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-10-26 — — CN disclosed
CN-112210368-A Composition for forming light-emitting layer, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2021-01-12 — — CN disclosed
CN-106905367-B Electron transport material or electron injection material, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-17 — — CN disclosed
CN-111909189-A Polycyclic aromatic compound, multimer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-10 — — CN disclosed
CN-108473511-B Polycyclic aromatic compound, material for organic device, light-emitting element, and device 学校法人关西学院 2020-11-06 — — CN disclosed
CN-111892615-A Polycyclic aromatic compound, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-11-06 — — CN disclosed
CN-107406759-B Polycyclic aromatic compound, composition for forming light-emitting layer, and use thereof 学校法人关西学院 2020-10-30 — — CN disclosed
CN-105431439-B Polycyclic aromatic compound, method for producing same, material for organic device, and application thereof 学校法人关西学院 2020-09-25 — — CN disclosed
CN-111662314-A Polycyclic aromatic compound or condensation polymer thereof, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2020-09-15 — — CN disclosed
CN-111527094-A Compound having boron as spiro atom and polymer compound thereof 学校法人关西学院 2020-08-11 — — CN disclosed
CN-111212844-A Polycyclic aromatic dimer compound 学校法人关西学院 2020-05-29 — — CN disclosed
CN-107735879-B Polycyclic aromatic compound, polycyclic aromatic polymer compound, composition for forming light-emitting layer, and use thereof 学校法人关西学院 2020-03-13 — — CN disclosed
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2019-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11407774-B2 Polycyclic aromatic compound ETV6, EML4, EBPL KDM4E 717/4885LMNA 1920/4885CYP1A2 3501/4885
US-20190256538-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, EBPL KDM4E 717/4885LMNA 1920/4885CYP1A2 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.