SCHEMBL2127406

SCHEMBL2127406

CC(O)COC(=O)CCS

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ADRA2A P08913 1/20 0.35
ADRA1A P35348 1/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
BLM P54132 1/20 0.34
LPAR6 P43657 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR4 Q99677 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
LPAR2 Q9HBW0 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822396 0.86 MAPT (0.67) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL29930756 0.84 MAPT (0.41) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL6738675 0.84 TSHR (0.43) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL996843 0.82 KDM4E (0.44) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822246 0.82 MAPT (0.74) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL821850 0.82 MAPT (0.81) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL451461 0.82
SCHEMBL6355099 0.81 MAPT (0.39) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL11367005 0.80 MAPT (0.60) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822254 0.80 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10961448-B2 Acid stabilization of quantum dot-resin concentrates and premixes NANOSYS, INC. (US) 2021-03-30 US claimed
WO-2018226654-A1 ACID STABILIZATION OF QUANTUM DOT-RESIN CONCENTRATES AND PREMIXES SMITH AUSTIN (US) 2018-12-13 WO claimed
US-20180345638-A1 ACID STABILIZATION OF QUANTUM DOT-RESIN CONCENTRATES AND PREMIXES NANOSYS, INC. (US) 2018-12-06 US claimed
US-9894946-B2 Method for modifying the surface of an elastomer product SEMPERIT AKTIENGESELLSCHAFT HOLDING (AT) 2018-02-20 US claimed
EP-2719720-B1 Method for modifying the surface of an elastomer product SEMPERIT AG HOLDING (AT) 2015-08-12 EP claimed
US-9056954-B2 Cathodic electrocoating compositions AXALTA COATING SYSTEMS IP CO., LLC (US) 2015-06-16 US claimed
EP-2719720-A1 Method for modifying the surface of an elastomer product Semperit Aktiengesellschaft Holding (AT) 2014-04-16 EP claimed
US-20140096307-A1 METHOD FOR MODIFYING THE SURFACE OF AN ELASTOMER PRODUCT SEMPERIT AKTIENGESELLSCHAFT HOLDING (AT) 2014-04-10 US claimed
US-20130146466-A1 CATHODIC ELECTROCOATING COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-06-13 US claimed
US-8440736-B2 Photocuable thiol-ene low gas permeability membranes UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-05-14 US claimed
US-20090253805-A1 Photocurable Thiol-Ene Low Gas Permeability Membranes UNIVERSITY OF SOUTHERN MISSISSIPPI 2009-10-08 US claimed
US-12043731-B2 Use of polyvinylacetate polymers or copolymers to increase the viscosity of the isocyanate component of a two-component curable polymeric system HENKEL AG & CO. KGAA (DE) 2024-07-23 US disclosed
WO-2024147917-A1 DIELECTRIC FILM FORMING COMPOSITION CONTAINING ACYL GERMANIUM COMPOUND FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2024-07-11 WO disclosed
WO-2024141334-A1 THIOL MASTERBATCH COMPOSITIONS AND METHODS OF PREPARING ULTRAVIOLET-CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-07-04 WO disclosed
EP-4393990-A1 THIOL MASTERBATCH COMPOSITIONS AND METHODS OF PREPARING ULTRAVIOLET-CURABLE COMPOSITIONS ARKEMA FRANCE (FR) 2024-07-03 EP disclosed
WO-2011140519-A2 IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION MEDICUS BIOSCIENCES, LLC (US) 2011-11-10 WO disclosed
US-20110195237-A1 SYSTEM AND RESIN FOR RAPID PROTOTYPING HUNTSMAN INTERNATIONAL LLC (US) 2011-08-11 US disclosed
EP-2346672-A1 SYSTEM AND RESIN FOR RAPID PROTOTYPING Huntsman Advanced Materials (Switzerland) GmbH (CH) 2011-07-27 EP disclosed
WO-2010043463-A1 SYSTEM AND RESIN FOR RAPID PROTOTYPING HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2010-04-22 WO disclosed
US-20090253805-A1 Photocurable Thiol-Ene Low Gas Permeability Membranes UNIVERSITY OF SOUTHERN MISSISSIPPI 2009-10-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253805-A1 Photocurable Thiol-Ene Low Gas Permeability Membranes ESD, TMT1A, GPX4 MAPT 2934/4885LMNA 3519/4885KDM4E 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.