Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21276267 | 0.90 | MGLL (0.49) | MGLL | |
| SCHEMBL21276318 | 0.89 | CYP3A4 (0.51) | CYP3A4USP2HIF1ACYP1A2CYP2D6 | |
| SCHEMBL21257996 | 0.89 | MGLL (0.50) | CYP3A4USP2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL21257971 | 0.84 | MGLL (0.54) | CYP3A4USP2CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL21276130 | 0.84 | CYP2D6 (0.62) | CYP3A4USP2HIF1AALDH1A1CYP1A2 | |
| SCHEMBL21276150 | 0.83 | USP2 (0.51) | CYP3A4USP2HIF1AALDH1A1CYP1A2 | |
| SCHEMBL20556565 | 0.83 | — | — | |
| SCHEMBL21276124 | 0.83 | MCHR1 (0.50) | CYP3A4USP2CYP1A2CYP2D6TSHR | |
| SCHEMBL21257983 | 0.83 | FAAH (0.53) | CYP3A4USP2CYP1A2CYP2D6TSHR | |
| SCHEMBL21257967 | 0.81 | CYP3A4 (0.51) | CYP3A4USP2HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | LUNDBECK LA JOLLA RESEARCH CENTER, INC. (US) | 2019-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385057-B2 | Pyrazole compounds and methods of making and using same | FAAH, FAAH2, MGLL | CYP3A4 193/4885USP2 2128/4885HIF1A 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.