SCHEMBL21281859

SCHEMBL21281859

Cc1ccc2c(-c3ccccc3)nc(Cl)nc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.79
▸ ALDH1A1 P00352 6/20 0.79
▸ MAPT P10636 5/20 0.79
▸ LMNA P02545 3/20 0.79
▸ L3MBTL1 Q9Y468 2/20 0.56
▸ KMT2A Q03164 3/20 0.50
▸ HPGD P15428 3/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ ADORA1 P30542 1/20 0.50
▸ OPRK1 P41145 1/20 0.50
▸ GLA P06280 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ ADORA2A P29274 1/20 0.46
▸ DHODH Q02127 2/20 0.46
▸ TP53 P04637 2/20 0.45
▸ NR1I2 O75469 1/20 0.45
▸ EGFR P00533 1/20 0.45
▸ ADRA2A P08913 1/20 0.45
▸ ADORA3 P0DMS8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13440492 0.89 KDM4E (1.00) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL18916876 0.83 KDM4E (0.61) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL29423640 0.83 KDM4E (1.00) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL15860248 0.83 KDM4E (1.00) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL15860237 0.83 ALDH1A1 (0.69) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL18456158 0.82 WHR1 (0.59) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL19483226 0.82 KDM4E (0.97) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL808420 0.81 KDM4E (0.77) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL14923033 0.80 KDM4E (0.64) KDM4EALDH1A1MAPTLMNAL3MBTL1
SCHEMBL15860242 0.79 KDM4E (0.73) KDM4EALDH1A1MAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-27 — — US disclosed
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2023-07-27 — — US disclosed
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2022-06-21 — — US disclosed
WO-2021230650-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-11-18 — — WO disclosed
WO-2019172623-A1 COMPOUND FOR ORGANIC ELECTRIC DEVICE, ORGANIC ELECTRIC DEVICE USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-09-12 — — WO disclosed
WO-2019160335-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2019-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240141-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF ESR1, GPX1, LEF1 KDM4E 1003/4885ALDH1A1 343/4885MAPT 1456/4885
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof ORAI2, KCNJ2, OR10J3 KDM4E 410/4885ALDH1A1 2536/4885MAPT 3503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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