Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14923034 | 0.89 | KMT2A (0.55) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL25820279 | 0.87 | KDM4E (0.53) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL12587959 | 0.84 | ALDH1A1 (0.47) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL18456158 | 0.81 | WHR1 (0.59) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL21281859 | 0.80 | KDM4E (0.79) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL17343522 | 0.79 | DHFR (0.53) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL13330654 | 0.79 | ALDH1A1 (0.58) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL17343516 | 0.79 | DHFR (0.53) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL31415566 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL31070213 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428586-B1 | Dimeric nucleic acid dyes, and associated systems and methods | BIOTIUM INC (US) | 2013-05-08 | — | — | EP | disclosed |