Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21283008 | 0.90 | KDM4E (0.36) | GHSRCYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL18868656 | 0.84 | KMT2A (0.43) | GHSRFOLH1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL21283007 | 0.78 | KMT2A (0.42) | GHSRFOLH1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL20748226 | 0.75 | PPARG (0.38) | CYP3A4KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL23398110 | 0.73 | KDM4E (0.41) | GHSRFOLH1CYP2C19KDM4EALDH1A1 | |
| SCHEMBL14429284 | 0.73 | KMT2A (0.43) | GHSRFOLH1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19854872 | 0.72 | LMNA (0.47) | GHSRFOLH1KDM4EALDH1A1LMNA | |
| SCHEMBL25778077 | 0.72 | CA1 (0.40) | CYP2C19KDM4EKMT2AHTTTACR1 | |
| SCHEMBL29890667 | 0.71 | TSHR (0.48) | KDM4EKMT2ATACR1 | |
| SCHEMBL13701516 | 0.71 | SGPL1 (0.40) | KMT2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723750-B2 | Sphingamide compounds and methods for binding iNKT cells | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190256541-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING iNKT CELLS | LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY (US) | 2019-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10723750-B2 | Sphingamide compounds and methods for binding iNKT cells | UGCG, CD4, CERT1 | GHSR 954/4885FOLH1 1855/4885CYP3A4 4363/4885 |
| US-20190256541-A1 | SPHINGAMIDE COMPOUNDS AND METHODS FOR BINDING iNKT CELLS | UGCG, CD4, CERT1 | GHSR 954/4885FOLH1 1855/4885CYP3A4 4363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.