SCHEMBL212848

SCHEMBL212848

CC(C)(C)N1c2ccccc2SC1S[N]

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.33
▸ BCHE P06276 2/20 0.31
▸ CYP3A4 P08684 1/20 0.30
▸ CYP2D6 P10635 1/20 0.30
▸ CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469462 0.88 MAOA (0.34) MAOABCHECYP3A4CYP2D6CYP2C19
SCHEMBL3477800 0.85 MAOA (0.32) MAOABCHE
SCHEMBL535563 0.85 MAOA (0.32) MAOABCHE
SCHEMBL7218615 0.79 BCHE (0.31) BCHE
SCHEMBL16726512 0.77 MAOA (0.36) MAOABCHECYP3A4CYP2D6CYP2C19
SCHEMBL16726439 0.77 MAOA (0.36) MAOABCHECYP3A4CYP2D6CYP2C19
SCHEMBL7935765 0.75 MAOA (0.35) MAOABCHECYP3A4CYP2D6CYP2C19
SCHEMBL6693472 0.74 MEN1 (0.33) —
SCHEMBL6690997 0.74 MGLL (0.33) —
SCHEMBL6693175 0.71 MAPT (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541634-B1 TIRE COMPRISING A TREAD COMPRISING A THERMOPLASTIC ELASTOMER AND A CROSSLINKING SYSTEM BASED ON SULFUR MICHELIN & CIE (FR) 2020-12-30 — — EP claimed
EP-3717561-A1 HIGH-MODULUS RUBBER COMPOSITION COMPRIISNG A VULCANISATION ULTRA-ACCELERATOR Compagnie Générale des Etablissements Michelin (FR) 2020-10-07 — — EP claimed
EP-3717279-A1 HIGH MODULUS RUBBER COMPOSITION COMPRISING AN EFFECTIVE SULFUR RETICULATION SYSTEM Compagnie Générale des Etablissements Michelin (FR) 2020-10-07 — — EP claimed
US-20190322136-A1 TIRE COMPRISING A TREAD COMPRISING A THERMOPLASTIC ELASTOMER AND A CROSSLINKING SYSTEM BASED ON SULFUR COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2019-10-24 — — US claimed
EP-3548304-A1 TYRE PROVIDED WITH AN OUTER SIDEWALL COMPRISING ONE OR MORE THERMOPLASTIC ELASTOMERS AND ONE OR MORE SYNTHETIC DIENE ELASTOMERS Compagnie Générale des Etablissements Michelin (FR) 2019-10-09 — — EP claimed
EP-3541634-A1 TYRE COMPRISING A TREAD COMPRISING A THERMOPLASTIC ELASTOMER AND A CROSSLINKING SYSTEM BASED ON SULFUR Compagnie Générale des Etablissements Michelin (FR) 2019-09-25 — — EP claimed
US-20130225757-A1 RUBBER COMPOSITION FOR TIRE SIDEWALL AND PNEUMATIC TIRE TOYO TIRE & RUBBER CO., LTD. (JP) 2013-08-29 — — US claimed
US-7442733-B2 Rubber composition comprising a citraconimidomaleimide MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2008-10-28 — — US claimed
US-20060247342-A1 Rubber composition comprising a citraconimidomaleimide MICHELIN RECHERCHE ET TECHNIQUE S.A. 2006-11-02 — — US claimed
US-7098260-B2 diene elastomer and a reinforcing filler; automobile tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2006-08-29 — — US claimed
EP-1499669-B1 SILOXANE POLYSULPHIDE USABLE AS CROSS-LINKING AGENT AND PROCESS FOR OBTAINING SUCH. MICHELIN SOC TECH (FR) 2006-01-11 — — EP claimed
US-20050090680-A1 usable for cross-linking elastomeric networks, in particular in the manufacture of tires or semi-finished products for tires. NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-04-28 — — US claimed
US-20050090606-A1 diene elastomer and a reinforcing filler; automobile tires MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2005-04-28 — — US claimed
EP-4267405-A1 RUBBER COMPOSITION COMPRISING A CRUMB RUBBER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-11-01 — — EP disclosed
EP-3840962-B1 TYRE HAVING A COMPOSITION COMPRISING AN ETHYLENE-RICH ELASTOMER, A PEROXIDE AND A SPECIFIC ACRYLATE DERIVATIVE MICHELIN & CIE (FR) 2023-10-04 — — EP disclosed
US-11753522-B2 Use of magnesium oxide for crosslinking polymers ARKEMA FRANCE (FR) 2023-09-12 — — US disclosed
US-20020077423-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION 2002-06-20 — — US disclosed
EP-1199331-A1 Polymaleimide-containing rubber composition and tire BRIDGESTONE CORPORATION (JP) 2002-04-24 — — EP disclosed
US-5665799-A REINFORCEMENT FIBERS, HYDROXY FLAVAN COMPOUND, QUINOLINE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-09-09 — — US disclosed
EP-0700959-A1 A rubber composition and a vulcanizing adhesion method using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-03-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050090680-A1 usable for cross-linking elastomeric networks, in particular in the manufacture of tires or semi-finished products for tires. TXN, TST, TERB1 MAOA 2846/4885BCHE 4370/4885CYP3A4 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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