Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 4/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290300 | 0.82 | DGAT1 (0.46) | DGAT1KDM1ALPLLIPGSNCA | |
| SCHEMBL21125909 | 0.81 | DGAT1 (0.67) | DGAT1LPLLIPGSNCA | |
| SCHEMBL29688083 | 0.80 | DGAT1 (0.67) | DGAT1LPLLIPGSNCA | |
| SCHEMBL2697886 | 0.80 | DGAT1 (0.67) | DGAT1LPLLIPGSNCA | |
| SCHEMBL6921637 | 0.79 | CSF1R (0.49) | LPLLIPGSNCACSF1R | |
| SCHEMBL30197526 | 0.79 | CSF1R (0.49) | LPLLIPGSNCACSF1R | |
| SCHEMBL21290175 | 0.79 | DGAT1 (0.56) | DGAT1KDM1ALPLLIPGSNCA | |
| SCHEMBL16787665 | 0.78 | DGAT1 (0.61) | DGAT1KDM1ALPLLIPGCSF1R | |
| SCHEMBL21125910 | 0.78 | DGAT1 (0.57) | DGAT1LPLLIPG | |
| SCHEMBL21290302 | 0.78 | MAPT (0.41) | DGAT1KDM1ASNCACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3601304-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |