Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | LPL | P06858 | 8/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | TDO2 | P48775 | 4/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290176 | 0.82 | DGAT1 (0.52) | DGAT1LPLLIPGSNCACSF1R | |
| SCHEMBL23018805 | 0.78 | LIPG (0.59) | DGAT1LPLLIPGSNCACA1 | |
| SCHEMBL21290304 | 0.76 | SNCA (0.53) | DGAT1LPLLIPGSNCACA1 | |
| SCHEMBL18015329 | 0.75 | LIPG (0.57) | DGAT1LPLLIPGSNCANPC1 | |
| SCHEMBL6921637 | 0.75 | CSF1R (0.49) | LPLLIPGSNCACSF1RCA1 | |
| SCHEMBL19933557 | 0.75 | LIPG (0.56) | DGAT1LPLLIPGSNCACA1 | |
| SCHEMBL30197526 | 0.75 | CSF1R (0.49) | LPLLIPGSNCACSF1RCA1 | |
| SCHEMBL21290177 | 0.75 | IDO1 (0.45) | DGAT1LPLLIPGIDO1TDO2 | |
| SCHEMBL21264517 | 0.75 | DGAT1 (0.54) | DGAT1LPLLIPGSNCACA1 | |
| SCHEMBL30536013 | 0.75 | DGAT1 (0.54) | DGAT1LPLLIPGSNCACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3601304-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |