Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25100914 | 0.84 | DGAT1 (0.37) | RAB9AMEN1KMT2ADGAT1KDM1A | |
| SCHEMBL21290301 | 0.82 | FPR2 (0.39) | MAPTRAB9AMEN1GAAKMT2A | |
| SCHEMBL26050415 | 0.82 | EGFR (0.43) | MEN1KMT2ADGAT1EGFRCYP3A4 | |
| SCHEMBL23956217 | 0.82 | DGAT1 (0.35) | DGAT1KDM1AEGFRFYN | |
| SCHEMBL21289786 | 0.81 | ERN1 (0.43) | MAPTRAB9AMEN1GAAKMT2A | |
| SCHEMBL21290169 | 0.81 | NPC1 (0.52) | RAB9AMEN1KMT2ADGAT1EGFR | |
| SCHEMBL15334799 | 0.79 | ACHE (0.47) | MAPTRAB9AMEN1KMT2AEGFR | |
| SCHEMBL21412245 | 0.78 | EGFR (0.36) | RAB9AMEN1KMT2AEGFRKDM4E | |
| SCHEMBL21290176 | 0.78 | DGAT1 (0.52) | DGAT1KDM1ACSF1RSNCA | |
| SCHEMBL12989617 | 0.78 | DGAT1 (0.33) | DGAT1KDM1AHDAC6EGFRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3601304-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |