Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290414 | 0.84 | PTGS1 (0.39) | PDK2PTGS1PTGS2DHODHL3MBTL1 | |
| SCHEMBL28405722 | 0.79 | PTGS1 (0.51) | SLC6A4SLC6A3PTGS1PTGS2ALDH1A1 | |
| SCHEMBL30171520 | 0.79 | PTGS1 (0.51) | SLC6A4SLC6A3PTGS1PTGS2ALDH1A1 | |
| SCHEMBL3621439 | 0.78 | MAPK1 (0.55) | PTGS1PTGS2CFTRALDH1A1ABL1 | |
| SCHEMBL21462378 | 0.77 | OPRK1 (0.46) | PDK2SLC6A4SLC6A3ALDH1A1KDM4E | |
| SCHEMBL1324766 | 0.77 | RPS6KB1 (0.46) | SLC6A4SLC6A3DHODHALDH1A1 | |
| SCHEMBL18816928 | 0.77 | DHODH (0.52) | SLC6A4SLC6A3PTGS1DHODHALDH1A1 | |
| SCHEMBL29335088 | 0.75 | NAPRT (0.42) | SLC6A4SLC6A3MAP2K1CFTRALDH1A1 | |
| SCHEMBL1807364 | 0.74 | NAPRT (0.61) | SLC6A4SLC6A3MAP2K1CFTRALDH1A1 | |
| SCHEMBL20850438 | 0.73 | KMT2A (0.49) | ALDH1A1TDP1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| US-20220098477-A1 | MONONUCLEAR IRIDIUM COMPLEXES CONTAINING THREE ORTHO-METALLATED BIDENTATE LIGANDS AND OPTICAL ORIENTATING ANISTROPHY | UDC IRELAND LIMITED (IE) | 2022-03-31 | — | — | US | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098477-A1 | MONONUCLEAR IRIDIUM COMPLEXES CONTAINING THREE ORTHO-METALLATED BIDENTATE LIGANDS AND OPTICAL ORIENTATING ANISTROPHY | ICOSLG, CCL11, CCR3 | PDK2 3110/4885SLC6A4 3244/4885SLC6A3 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.