SCHEMBL21293949

SCHEMBL21293949

CC1(C)CCC(C)(C)c2cc3c(cc21)CCC3O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 1/20 0.36
DRD2 P14416 1/20 0.36
HTR7 P34969 1/20 0.36
ESR1 P03372 8/20 0.35
ESR2 Q92731 6/20 0.35
LMNA P02545 5/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
G6PD P11413 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
DAB2IP Q5VWQ8 1/20 0.35
ADCY10 Q96PN6 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HSD17B10 Q99714 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8312308 0.71 MTNR1A (0.39)
SCHEMBL6938404 0.71 RARB (0.37) CYP3A4RXRA
SCHEMBL6936021 0.71 UGT2B17 (0.44) CHRM4DRD2HTR7MEN1MAPT
SCHEMBL29605579 0.69 RARB (0.31) RXRA
SCHEMBL21776990 0.69 RARB (0.31) RXRA
SCHEMBL8309889 0.68 FFAR1 (0.46) RXRA
SCHEMBL8309891 0.68 FFAR1 (0.46) RXRA
SCHEMBL17571270 0.68 UGT2B17 (0.46) CHRM4DRD2HTR7KMT2APGR
SCHEMBL836185 0.68 UGT2B17 (0.46) CHRM4DRD2HTR7KMT2APGR
SCHEMBL17571271 0.68 UGT2B17 (0.46) CHRM4DRD2HTR7KMT2APGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715682-B Polymerization catalyst 尤尼威蒂恩技术有限责任公司 2022-09-30 CN disclosed
EP-3519465-B1 POLYMERIZATION CATALYSTS UNIVATION TECH LLC (US) 2022-06-29 EP disclosed
US-10982024-B2 Polymerization catalysts UNIVATION TECHNOLOGIES, LLC (US) 2021-04-20 US disclosed
US-20190263944-A1 POLYMERIZATION CATALYSTS UNIVATION TECHNOLOGIES, LLC (US) 2019-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10982024-B2 Polymerization catalysts HACL2, ARL1, NSFL1C CHRM4 2010/4885DRD2 3271/4885HTR7 4001/4885
US-20190263944-A1 POLYMERIZATION CATALYSTS HACL2, ARL1, NSFL1C CHRM4 2164/4885DRD2 3330/4885HTR7 4035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.