Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309891 | 0.82 | FFAR1 (0.46) | — | |
| SCHEMBL8309889 | 0.82 | FFAR1 (0.46) | — | |
| SCHEMBL8311004 | 0.81 | ACHE (0.37) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8311006 | 0.81 | ACHE (0.37) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8308287 | 0.80 | RXRA (0.35) | — | |
| SCHEMBL6037041 | 0.72 | RXRA (0.52) | — | |
| SCHEMBL21293949 | 0.71 | CHRM4 (0.36) | — | |
| SCHEMBL5172930 | 0.71 | SIGMAR1 (0.61) | — | |
| SCHEMBL6939291 | 0.69 | RXRA (0.36) | — | |
| SCHEMBL8308767 | 0.69 | RXRA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933351-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| EP-0933350-A1 | Tricyclic retinoids, methods for their production and use | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-08-04 | — | — | EP | disclosed |
| US-5770382-A | RETINOIC ACID AND RETINOID X RECEPTOR AGONISTS; TREATINGSKIN, EYE, BRAIN, AND CARDIOVASCULAR DISORDERS; CANCER | LIGAND PHARMACEUTICALS, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5770378-A | A VITAMINE A METABOLITE, POTENT DRUGS TREATING SKIN DISEASES, CANCER, EYE DISEASES, CARDIOVASCULAR DISORDERS | LIGAND PHARMACEUTICALS, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| US-5770383-A | ACTIVATE RETINOID RECEPTORS | LIGAND PHARMACEUTICALS, INC. (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0800504-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS, INC. (US) | 1997-10-15 | — | — | EP | disclosed |
| US-5612178-A | Method of quantitative enzyme determination | ABBOTT LABORATORIES (US) | 1997-03-18 | — | — | US | disclosed |
| WO-1996020914-A1 | TRICYCLIC RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1996-07-11 | — | — | WO | disclosed |
| EP-0315058-B1 | Method for self-performing enzyme kinetics | ABBOTT LAB (US) | 1994-06-22 | — | — | EP | disclosed |
| EP-0315058-A2 | Method for self-performing enzyme kinetics | ABBOTT LABORATORIES (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4801535-A | DETECTION OF ASPARTATE AMINOTRANSFERASE | XYTRONYX, INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0263145-A4 | METHOD FOR DETECTION OF PERIODONTAL DISEASE. | XYTRONYX INC (US) | 1989-01-26 | — | — | EP | disclosed |
| EP-0263145-A1 | METHOD FOR DETECTION OF PERIODONTAL DISEASE | XYTRONYX, INC. (US) | 1988-04-13 | — | — | EP | disclosed |
| WO-1987005633-A1 | METHOD FOR DETECTION OF PERIODONTAL DISEASE | XYTRONYX, INC. (US) | 1987-09-24 | — | — | WO | disclosed |