Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.37 |
| ▸ | RARG | P13631 | 9/20 | 0.37 |
| ▸ | RARA | P10276 | 7/20 | 0.37 |
| ▸ | RXRA | P19793 | 13/20 | 0.36 |
| ▸ | RXRB | P28702 | 10/20 | 0.36 |
| ▸ | RXRG | P48443 | 7/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599145 | 0.72 | RXRA (0.42) | RARBRARGRARARXRARXRB | |
| SCHEMBL21776990 | 0.72 | RARB (0.31) | RARBRARGRARARXRARXRB | |
| SCHEMBL21293949 | 0.71 | CHRM4 (0.36) | RXRACYP3A4 | |
| SCHEMBL8308767 | 0.70 | RXRA (0.36) | RARBRARGRARARXRARXRB | |
| SCHEMBL5009416 | 0.70 | RXRA (0.41) | RARBRARGRARARXRARXRB | |
| SCHEMBL6939291 | 0.70 | RXRA (0.36) | RARBRARGRARARXRARXRB | |
| SCHEMBL15347776 | 0.69 | RXRA (0.50) | RARBRARGRARARXRARXRB | |
| SCHEMBL23343811 | 0.67 | DRD2 (0.54) | CYP26A1 | |
| SCHEMBL3961628 | 0.67 | DRD2 (0.54) | CYP26A1 | |
| SCHEMBL6250546 | 0.67 | BRD4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157047-B1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORP NORTH AMERICA INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6479424-B1 | FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1157047-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP Corporation North America Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035975-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. (US) | 2000-06-22 | — | — | WO | disclosed |