SCHEMBL2129396

SCHEMBL2129396

O=C1OC(=O)c2c(F)c(Oc3c(F)c(F)c(Oc4c(F)c(F)c5c(c4F)C(=O)OC5=O)c(F)c3F)c(F)c(F)c21

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15695594 1.00 KDM4E (0.34) KDM4EMAPTCRHBPCRHR2TSHR
SCHEMBL3956387 0.90 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL23266621 0.88
SCHEMBL15801312 0.88
SCHEMBL2128901 0.86 CA12 (0.42) KDM4EMAPTCRHBPCRHR2ALDH1A1
SCHEMBL15697316 0.85 CYP2C9 (0.31) TSHR
SCHEMBL14138381 0.82 HSD17B10 (0.37) KDM4ETSHRALDH1A1
SCHEMBL335922 0.79 ALDH1A1 (0.43) MAPTTSHRALDH1A1
SCHEMBL2608880 0.76
SCHEMBL9807348 0.76 TSHR (0.41) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound FUJIFILM CORPORATION (JP) 2023-11-07 US disclosed
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
WO-2021014821-A1 M-PHENYLENEDIAMINE COMPOUND, POLYMER AND METHOD FOR PRODUCING SAME, GAS SEPARATION MEMBRANE USING THIS POLYMER, GAS SEPARATION MODULE AND GAS SEPARATION APPARATUS 富士フイルム株式会社 2021-01-28 WO disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-10345748-B2 Sliding member, sliding member for fixing device, fixing device, and image formation apparatus Konica Minolta, Inc. (JP) 2019-07-09 US disclosed
US-20190176081-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2019-06-13 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-20190076777-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-14 US disclosed
US-10040035-B2 Gas separation membrane, gas separation module, gas separation device, and gas separation method FUJIFILM CORPORATION (JP) 2018-08-07 US disclosed
US-20070041699-A1 Fluorinated polyamide acid resin composition for optical materials NIPPON SHOKUBAI CO., LTD. (JP) 2007-02-22 US disclosed
US-20070041699-A1 Fluorinated polyamide acid resin composition for optical materials NIPPON SHOKUBAI CO., LTD. (JP) 2007-02-22 US disclosed
US-20070041699-A1 Fluorinated polyamide acid resin composition for optical materials NIPPON SHOKUBAI CO., LTD. (JP) 2007-02-22 US disclosed
US-20060142539-A1 Method for production of fluorinated phenylenediamine NIPPON SHOKUBAI CO., LTD. (JP) 2006-06-29 US disclosed
EP-1640370-A1 BIS (FLUORINE-CONTAINING PHTHALIC ANHYDRIDE) AND METHOD FOR PRODUCTION THEREOF Nippon Shokubai Co., Ltd. (JP) 2006-03-29 EP disclosed
US-6924348-B2 Polyamide acid and polyimide, and optical material NIPPON SHOKUBAI CO., LTD. (JP) 2005-08-02 US disclosed
US-20050020839-A1 Fluorinated bis(phthalic anhydride) and method for producing the same NIPPON SHOKUBAI CO., LTD. (JP) 2005-01-27 US disclosed
US-20040234686-A1 Method and apparatus for production of fluorine-containing polyimide film NIPPON SHOKUBAI CO., LTD. (JP) 2004-11-25 US disclosed
US-20030050407-A1 Polyamide acid and polyimide, and optical material NIPPON SHOKUBAI CO., LTD (JP) 2003-03-13 US disclosed
EP-1275679-A1 Polyamide acid and polyimide, and optical material Nippon Shokubai Co., Ltd. (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020839-A1 Fluorinated bis(phthalic anhydride) and method for producing the same FHIT, PBRM1, INF2 KDM4E 2903/4885MAPT 541/4885CRHBP 4609/4885
US-11806661-B2 Polymer and method for producing the same, gas separation membrane, gas separation module, and gas separation apparatus using the polymer, and m-phenylenediamine compound PRMT9, PRMT1, PNMT KDM4E 1786/4885MAPT 3637/4885CRHBP 1379/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.