SCHEMBL21295728

SCHEMBL21295728

[c]1ccc2cc(-c3ccncc3)oc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.41
QPCT Q16769 1/20 0.40
HIF1A Q16665 1/20 0.39
SHBG P04278 1/20 0.38
MAOB P27338 1/20 0.37
DYRK1A Q13627 1/20 0.37
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CFTR P13569 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CYP19A1 P11511 1/20 0.35
PTK2 Q05397 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CDC7 O00311 1/20 0.34
ADORA2A P29274 1/20 0.34
PIK3CB P42338 2/20 0.33
TYR P14679 1/20 0.33
PTGS1 P23219 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16720104 0.87 GSK3B (0.41) GSK3BQPCTHIF1ASHBGMAOB
SCHEMBL11492182 0.83 MAOB (0.49) SHBGMAOBCYP1A1CYP1A2CYP1B1
SCHEMBL21295874 0.81 CYP2A6 (0.42) CYP1A1CYP1A2CYP1B1CYP19A1TP53
Pyridarone SCHEMBL29993452 0.75 MAOB (0.62) MAOBCYP1A1CYP1A2POLBCFTR
Pyridarone SCHEMBL2109298 0.75 MAOB (0.62) MAOBCYP1A1CYP1A2POLBCFTR
SCHEMBL21295711 0.73 AHR (0.47) HIF1ACYP1A1CYP1A2POLBCYP1B1
SCHEMBL10901632 0.71 SHBG (0.46) GSK3BQPCTHIF1ASHBGCYP1A1
SCHEMBL10899360 0.71 MAOB (0.51) GSK3BQPCTHIF1ASHBGMAOB
SCHEMBL8908733 0.70 ALOX5 (0.31) SHBGMAOB
SCHEMBL10899406 0.69 HIF1A (0.50) GSK3BQPCTHIF1ASHBGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed